Use of IL-10 to stimulate peripheral blood mononuclear cell cyto

Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin

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424 851, 530351, 514 21, A61K 4505

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active

058717250

ABSTRACT:
This invention relates to the use of IL-10, alone or in combination with IL-2 and/or .alpha.-IFN, to treat neoplastic disorders by stimulating cytolytic activity of peripheral blood mononuclear cells with IL-10 alone.

REFERENCES:
patent: 4690915 (1987-09-01), Rosenberg
patent: 5776451 (1998-07-01), Hsu et al.
Rosenberg et al., The New England J. Med., vol. 319 (25), pp. 1676-1680, 1988.
Gemlo et al., Cancer Res., vol. 48, pp. 5864-5867, 1988.
Spirts et al., Int. Arch. Allergy Immunol., vol. 99, pp. 8-15, 1992.
Malefyt et al., Current Opinion in Immunol., vol. 4, pp. 314-320, 1992.
Howard et al., J. Clin. Immunol., vol. 12 (4), pp. 239-247, 1992.
Kedar, et al. Cancer Immun. Immunotherapy 35: 63-68 (1992).
Spagnoli, et al. Cellular Immun. 146: 391-405 (1993).
Chen et al. J. Immunol. 147 : 528 (1991).
Edwards et al., Cancer Res. 52 : 3425 (1992).
Hsu et al., International Immunol. 4 : 563 (1992).
Kedar et al. Cancer Immunol. Immunother. 35:63 (1992).
Lotze et al. Keystone Symposia on Molecular & Cellular Biology, Jan. 26 -Feb. 10, 1993 (distributed Jan. 26, 1993).
Mule' et al. J. Immunol. 135:1 (1985).
Nagler et al. J. Immunol. 141: 2349 (1988).
Phillips et al., J. Clin. Oncol. 5: 1933 (1987).
Rosenberg, Can. Treat. Rep. 68: 233 (1984).
Spits et al. J. Immunol. 141: 29 (1988).
Swisher et al., Cell. Immunol. 128: 450 (1990).
Tepper et al., Cell 57: 503 (1989).
Thomas et al. Eur. J. Cancer 28A: 1047 (1992).
Thompson -Snipes et al., J. Exp. Med. 173: 507 (1991).

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