Use of hydroxychloroquine for treatment of graft-versus-host dis

Details Use of hydroxychloroquine for treatment of graft-versus-host dis Use of hydroxychloroquine for treatment of graft-versus-host dis

1993-10-29

1995-09-26

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514885, A61K 3147

Patent

active

054534313

ABSTRACT:
The present invention provides methods of treating graft-versus-host disease comprising administering to a patient having graft-versus-host disease an effective mount of hydroxychloroquine. The present invention aim provides a method of suppressing alloreactivity arising from reactions of donor T lymphocytes against recipient cells comprising administering to said cells an amount of hydroxychloroquine effective to suppress such alloreaetivity.

REFERENCES:
patent: 2546658 (1951-03-01), Surrey
patent: 4419352 (1983-12-01), Cox et al.
patent: 4657763 (1987-04-01), Finkelstein
patent: 4968702 (1990-11-01), Poletto et al.
patent: 5242687 (1993-09-01), Tykoinski et al.
patent: 5262424 (1993-11-01), Kao
patent: 5314894 (1994-05-01), Seder et al.
patent: 5330993 (1994-07-01), Armistead et al.

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