Use of hydrophobic interaction chromatography to purify polyethy

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Aftertreated polymer

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424 7808, 210635, 210656, 530351, A61K 31795, B01D 1508, C08G 6500

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active

059355646

ABSTRACT:
The present invention relates to a process for purifying polyethylene glycols (PEGs) which utilizes hydrophobic interaction chromatography (HIC) to separate the PEGs based on their size and on their end-group functionality. The purified PEGs can be used to modify biologically active molecules and improve overall production of such molecules.

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