Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1993-02-23
1996-10-08
Wityshyn, Michael G.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
4352403, 435 2, 600 33, 600 34, 514 8, 514 12, 514 21, 424 937, 424559, 424561, C12N 500, A01N 102, A61B 17435, A61K 3800, A61K 3816, A61K 3548, A61K 3552, A61K 3554
Patent
active
055630596
ABSTRACT:
A method is provided for increasing the fertilization potential of oocytes comprising culturing oocytes in vitro with an effective amount of inhibin, activin, or a combination of inhibin and activin. Preferably the oocytes being cultured are immature. After the culturing step, the oocytes can be fertilized. The oocytes are suitably cryopreserved and thawed before the culturing step.
REFERENCES:
patent: 4845077 (1989-07-01), Hodgen
patent: 5102868 (1992-04-01), Woodruff et al.
patent: 5166190 (1992-11-01), Mather et al.
patent: 5206160 (1993-04-01), Takahashi et al.
Byrd, "Gamete Intrafallopian Transfer (Gift)", In Vitro Fertilization and Embryo Transfer: A manual of basic techniques (D. P. Wolf, ed.), Plenum Press, 265-279, (1988).
Gerrity et al., "Embryo Transfer", In Vitro Fertilization and Embryo Transfer: A manual of basic techniques (D. P. Wolf, ed.), Plenum Press, 189-207, (1988).
Malloy et al., "A laparoscopic approach to a program of gamete intrafallopian transfer", Fertil. Steril., 47(2):289 (1987).
Quigly et al., "Follicular size and number in human in vitro fertilization", Fertil. Steril., 38(6):678 (1982).
Yovich et al., "Pregnancies following pronuclear stage tubal transfer", Fertil. Steril., 48(5):851-857, (1987).
Hutchinson et al., BBRC, 146(3):1405-1412 (1987), "Effects of Bovine Inhibin, Transforming Growth Factor-.beta. and Bovine Activin-A on Granulosa Cell Differentiation".
Ying et al., BBRC, 136(3):969-975 (1986), "Inhibin and Beta Type Transforming Growth Factor have Opposite Modulating Effects on the Follicle Stimulating Hormone (FSH)-Induced Aromatase Activity . . . ".
Adashi & Resnick, Endocrinol., 119(4):1879-1881 (1986), "Antagonistic Interactions of Transforming Growth Factors in the Regulation of Granulosa Cell Differentiation".
Ignotz & Massague, J. Biol. Chem., 261(9):4337-4345 (1986), "Transforming Growth Factor-.beta. Stimulates the Expression of Fibronectin and Collagen and Their Incorporation into the Extracellular Matrix".
deKretser & Robertson, Biol. of Reprod., 40:33-47 (1989), "The Isolation and Physiology of Inhibin and Related Proteins".
Hsueh et al., PNAS USA, 84:5082-5086 (1987), "Heterodimers and Homodimers of Inhibin Subunits have Different Paracrine Action in the Modulation of Luteinizing Hormone-Stimulated Androgen Biosynthesis".
Hillier et al., J. Clin. Endocr. Metab., 72(6):1206-1211 (1991), "Effect of Recombinant Activin on Androgen Synthesis in Cultured Human Thecal Cells".
Hillier et al., Mol. Cell. Endocr., 75:R1-R6 (1991), "Effect of Recombinant Inhibin on Androgen Synthesis in Cultured Human Thecal Cells".
Bramley et al., J. Endocrin., 134:341-352 (1992), "Apparent .alpha.-inhibin subunit immunoactivity in porcine and ovine luteal extracts is due to interference by cytosolic proteases in the assay".
McLachlan et al., Fert. and Steril., 48(6):1001-1005 (1987), "Circulating immunoactive Inhibin in the Luteal Phase and Early Gestation of Women Undergoing Ovulation Induction".
Lee et al., Science, 243:396-398 (1989), "Secretion of Activin by Interstitial Cells in the Testis".
Mitrani et al., Cell, 63:495-501 (1990), "Activin can induce the formation of axial structures and is expressed in the hypoblast of the chick".
Mather et al., Endocrin., 127:3206-3214 (1990), "Activin stimulates spermatogonial proliferation in germ-sertoli cell cocultures from immature rat testis".
Smith et al., Nature, 345:729-731 (1990), "Identification of a potent xenopus mesoderm-inducing factor as a homologue of activin A".
Sugino et al., BBRC, 153:281-288 (1988), "Erythroid differentiation factor can modulate follicular granulosa cell functions".
Whittemore et al., Am. J. Epidemiol., 136:1184-1203 (1992), "Characteristics relating to ovarian cancer risk: Collaborative analysis of 12 US case-control studies".
Sathananthan et al. in Ultrastructure of the Ovary, Familiari et al., eds., Kluwer Academic Publ., Norwell, MA 1991, pp. 29-43, "Maturation of the human oocyte".
Lee et al. in The Molecular and Cellular Endocrinology of the Testis, Serono Symposia Publications from Raven Press, Cooke et al., eds., 1988, 50: 21-27, "Interstitial Cell Cultures Secrete and Activity with . . . ".
Lee and Gibson, Aust. J. Biol. Sci., 38:115-120 (1985), "Ovulation Rate and Inhibin Levels in Gonadotrophin-treated mice".
Baird et al., Ann. NY. Acad. Sci., 541:153-161 (1988), "Inhibin Levels in Gonadotropin-Treated Cycles".
Sheth et al., Adv. Contracept., 2:131-139 (1986), "Potential Application of Inhibin in Male and Female Contraception".
Franchimont et al., Rev. Fr. Gynecol. Obstet, 83(10):607-611 (1988), "Inhibin and Related Peptides: Mechanisms of Action and Regulation of Secretion".
Woodruff et al. in Growth Factors and the Ovary, Hirshfield, ed., Plenum Press, NY (1989), 291-295, "Modulation of Rat Inhibin mRNAs in Preovulatory and Atretic Follicles".
Osborn et al., J. Reprod. Fert., Suppl. 36:59-72 (1988), "An assessment of the factors causing embryonic loss after fertilization in vitro".
Sathananthan et al. in Ultrastructure of human gametogenesis and early embryogenesis, van Blerkom et al., eds., Kluwer Academic Publishers, 1989, pp. 181-199, "Effects of culture and cryopreservation on human oocyte . . . ".
Trounson in Clinical in vitro fertilization, 2nd Ed., Wood et al., eds., Springer-Verlag, 1989, pp. 33-50, "Fertilization and embryo culture".
Trounson in Clinical in vitro fertilization, 2nd Ed., Wood et al., eds., Springer-Verlag, 1989, pp. 127-142, "Embryo cryopreservation".
Trounson et al., J. Reprod. Fert., 64:285-294 (1982), "Effect of delayed insemination on in-vitro fertilization, culture and transfer of human embryos".
Al-Obaidi et al., J. Reprod. Fert., 81:403-414 (1987), "Reproductive Charracteristics of Lambs Actively Immunized Early in Life with Inhibin-enriched Preparations from Follicular Fluid of Cows".
Cummins et al., J. Reprod. Fert., 77:365-372 (1986), "Increase in Ovulation rate After Immunization of Merino Ewes with a Fraction of Bovine Follicular Fluid Containing Inhibin Activity".
Bremner et al., J. Clin. Invest., 68:1044-1052 (1981), "Follicle-Stimulating Hormone and Human Spermatogenesis".
Henderson et al., J. Endocrin., 102:305-309 (1984), "Increase in Ovulation Rate After Active Immunization of Sheep with Inhibin Partially Purified from Bovine Follicular Fluid".
Forage et al., J. Endocrin., 114:R1-R4 (1987), "Immunization Against an Inhibin Subunit Produced by Recombinant DNA Techniques Results in Increased Ovulation Rate in Sheep".
Sathananthan et al., Gamete Res., 5:191-198 (1982), "Ultrastructural observations on cortical granules in human follicular oocytes cultured in vitro".
Baker et al., Clin. Reprod. and Fert., 2:161-174 (1983), "Present Status of Research on Inhibin: An Appraisal".
Hasegawa et al. in Inhibin-non-steroidal regulation of follicle stimulating hormone secretion, Serono Publ., Raven Press, Burger et al., eds., 42:119-133 (1987), "Changes in serum concentrations of inhibin during the . . . ".
Sathananthan et al., Gamete Res., 16:343-354 (1987), "Morphology and Fertilizability of Frozen human oocytes".
Lefevre et al., Fert. and Steril., 46(2):325-327 (1986), "Absence of Predictive Value of Follicular Inhibin on the Results of Human in vitro Fertilization".
Al-Hasani et al., Human Reprod., 2:695-700 (1987), "Cryopreservation of human oocytes".
Findlay, Fertil. and Steril., 46(5):770-783 (1986), "The Nature of Inhibin and its Use in the Regulation of Fertility and Diagnosis of Infertility".
Woodruff et al., Science, 239:1296-1299 (1988), "Dynamic Changes in Inhibin Messenger RNAs in Rat Ovarian Follicles During the Reproductive Cycle".
Woodruff et al., Endocrin., 124:2193-2199 (1989), "Decreased inhibin gene expression in preovulatory follicles requires primary gonadotropin surges".
Rivier et al., Science, 234:205-208 (1986), "Inhibin-mediated feedback control of follicle-stimulating hormone secretion in the female rat".
D'Agostino et al., Endocrin., 124:310-317 (1989), "Unilateral ovariectomy increase inhibin messenger ribonucleic acid levels in newly recruited follicles".
DePaolo et al., Proc. Soc. Exp. Biol. &
Alak Baha M.
Stouffer Richard L.
Wolf Don P.
Woodruff Teresa K.
Dadio Susan M.
Genentech Inc.
Hasak Janet E.
Medical Research Foundation of Oregon
Wityshyn Michael G.
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