Use of hollow microcapsules in diagnosis and therapy

Details Use of hollow microcapsules in diagnosis and therapy Use of hollow microcapsules in diagnosis and therapy

1997-10-17

1999-10-05

Manuel, George

Surgery

Diagnostic testing

Detecting nuclear, electromagnetic, or ultrasonic radiation

A61B 800

Patent

active

059614595

ABSTRACT:
A diagnostic method analyses the effect of intervention, e.g. by surgery, especially in the myocardium. (i) Hollow microcapsules are administered into a blood vessel of a patient having a perfusion defect, (ii) if desired, an ultrasonic image is formed of the tissue, (iii) the occlusion is at least partially removed such that the blood flow in at least one area of the tissue is increased, and (iv) an ultrasonic image of the tissue is obtained after treatment. This is based on the observation of the particular properties of the microcapsules in the myocardium. It is also the basis of providing appropriate drugs to that site.

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patent: 5199951 (1993-04-01), Spears
patent: 5518709 (1996-05-01), Sutton et al.
Zhang, Y. Y. et al., "Nitrosation of Tryptophan Residue(s) in Serum Albumin and Model Dipeptides," J. Biol. Chem. 271 ( 24):14271-14279 (1996).

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