Use of heterocyclic inhibitors of serine proteases

Details Use of heterocyclic inhibitors of serine proteases Use of heterocyclic inhibitors of serine proteases

1990-03-26

1992-04-28

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514432, 514459, 514460, A61K 3135

Patent

active

051090180

ABSTRACT:
Certain novel heterocyclic compounds, their preparation, and their use in inhibiting serine proteases with chymotrypsin-like, elastase-like, and trypsin-like specificity and in the treatment of diseases such as emphysema which involve tissue proteolysis.

REFERENCES:
patent: 4036964 (1977-07-01), Buckle et al.
Chemical Abstracts (Waki et al) 95:161781g (1981).
Davies and Poole, J. Chem. Soc., pp. 1616-1629 (1928).
Milevskaya, Belinskaya, and Yagupol'skii, Zurh. Org. Kmim 9, pp. 2145-2149 (1973).
Tirodkar and Usgaonkar, Ind. J. Chem. 7, pp. 1114-1116 (1969).
Choksey and Usgaonkar, Ind. J. Chem. 14B, pp. 496-598 (1976).
Knott, J. Chem. Soc., pp. 402-410 (1963).
Powers, Ad. in Chem., 198, pp. 347-367 (1982).

Affiliated with

Also associated with

Rating

Use of heterocyclic inhibitors of serine proteases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of heterocyclic inhibitors of serine proteases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of heterocyclic inhibitors of serine proteases will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1249718