Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-12-26
2006-12-26
Romeo, David S (Department: 1647)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S399000, C435S377000
Reexamination Certificate
active
07153828
ABSTRACT:
Ligands which bind to the HER2, HER3 and/or HER4 receptors are useful as normal epithelial cell growth factors.
REFERENCES:
patent: 4935341 (1990-06-01), Bargmann et al.
patent: 4968603 (1990-11-01), Slamon et al.
patent: 5183884 (1993-02-01), Kraus et al.
patent: 5288477 (1994-02-01), Bacus et al.
patent: 5367060 (1994-11-01), Vandlen et al.
patent: 5401638 (1995-03-01), Carney et al.
patent: 5464751 (1995-11-01), Greene et al.
patent: 5578482 (1996-11-01), Lippman et al.
patent: 5686415 (1997-11-01), Carnahan et al.
patent: 5720954 (1998-02-01), Hudziak et al.
patent: 5772997 (1998-06-01), Hudziak et al.
patent: 5840525 (1998-11-01), Vandlen et al.
patent: 6015567 (2000-01-01), Hudziak et al.
patent: 6033660 (2000-03-01), Mather et al.
patent: 6096873 (2000-08-01), Schaefer et al.
patent: 6165464 (2000-12-01), Hudziak et al.
patent: 6500941 (2002-12-01), Schaefer et al.
patent: 2004/0258685 (2004-12-01), Brunetta et al.
patent: 444961 (1991-09-01), None
patent: 505148 (1992-09-01), None
patent: 0 599 274 (1994-06-01), None
patent: WO 87/07646 (1988-02-01), None
patent: WO 89/10412 (1989-11-01), None
patent: WO 91/15230 (1991-10-01), None
patent: WO 92/18627 (1992-10-01), None
patent: WO 92/20798 (1992-11-01), None
patent: WO 93/22424 (1993-11-01), None
patent: WO 94/00140 (1994-01-01), None
patent: WO 94/04560 (1994-03-01), None
patent: WO 94/08007 (1994-04-01), None
patent: WO 94/28133 (1994-08-01), None
patent: WO 94/26298 (1994-11-01), None
patent: WO 95/32724 (1995-12-01), None
patent: WO 96/15244 (1996-05-01), None
patent: WO 96/30403 (1996-10-01), None
patent: WO 98/02541 (1998-01-01), None
patent: WO 98/35036 (1998-08-01), None
Patel et al., Am. J. Respiratory Cell and Molecular Biol. vol. 22, pp. 432-440, Apr. 2000.
Crystal, RG., (JAMA, vol. 285(5): 612-618) Feb. 7, 2001.
Carraway & Cantley, “ANeuAcquaintance for ErbB3 and ErbB4: A Role for Receptor Heterodimerization in Growth Signaling.”Cell78: 5-8 (Jul. 15, 1994).
Carter et al., “Humanization of an Anti-p185\supHER2\nor Antibody for Human Cancer Therapy.”Proc. Natl. Acad. Sci. USA89: 4285-4289 (May 1992).
Carter et al., “Towards an Immunotherapy for p185\supHER2\nor Overexpression Tumors.”Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment, R.L. Ceriani, ed., New York: Plenum Press pp. 83-94 (1994).
Cole et al., “The EBV-Hybridoma Technique and its Application to Human Lung Cancer.”Monoclonal Antibodies and Cancer Therapy, New York: Alan R. Liss, Inc. pp. 77-96 (1985).
Dillman, R., “Antibodies as Cytotoxic Therapy.”J. Clin. Oncol.12(7): 1497-1515 (Jul. 1994).
Drebin et al., “Development of Monoclonal Antibodies Reactive with the Product of the neu Oncogene.”Symposium on Fundamental Cancer Research38: 277-289 (1986).
Sato et al., “Biological Effects in vitro of Monoclonal Antibodies to Human Epidermal Growth Factor Receptors.”Mol. Biol. Med.1: 511-529 (1983).
Taetle et al., “Effects of Anti-Epidermal Growth Factor (EGF) Receptor Antibodies and an Anti-EGF Receptor Recombinant-Ricin A Chain Immunoconjugate on Growth of Human Cells.”J. Natl. Cancer Inst.80(13): 1053-1059 (1988).
Patel, N.V. et al., “Heregulin (HRG) and human epideral receptor (HER) 2 and 3 are modulated duringin vitrohuman lung growth and differentiation,”Jour. of Invest. Med., (XP-002113357), vol. 45, No. 3, pp. 284A (1997).
Brockes et al , “Glial growth factor-like activity in Schwann Cell tumors”,Annals of Neurology, 20:317-322 (1986).
Brockes et al , “Purification and preliminary characterization of a glial growth factor from the bovine pituitary”,Journal of Biological Chemistry, 255(18):8374-8377 (1980).
Brockes et al , “Assay and isolation of glial growth factor from the bovine pituitary”,Methods in Enzymology, 147:217-223 (1987).
Carraway et al., “The erbB3 gene product is a receptor for heregulin”,Journal of Biological Chemistry, 269(19):14303-14306 (1994).
Corfas & Fischback, “The number of Na+ channels in cultured chick muscle is increased by ARIA, an acetylcholine receptor-inducing activity”,J. Neuroscience, 13(5):2118-2125 (1993).
Danilenko et al., “Neu differentiation factor (NDF) accelerates epidermal migration and differentiation in excisional wounds”FASEB, 8(4-5):abst. no. 3101, p. A535 (1994).
Danilenko et al, “Neu Differentiation Factor Upregulates Epidermal Migration and Integrin Expression in Excisional Wounds”,Journal of Clinical Investigation, 95(2):842-851 (1995).
Falls et al., “ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the Neu ligand family”,Cell, 72:801-815 (1993).
Fendly et al., “Characterization of Murine Monoclonal Antibodies Reactive to Either the Human Epidermal Growth Factor Receptor or HER2
eu Gene Product”,Cancer Research, 50:1550-1558 (Mar. 1, 1990).
Ho, W. et al., “Sensory and Motor Neuron-derived Factor”Journal of Biological Chemistry, 270(24):14523-14532 (Jun. 16, 1995).
Holmes et al., “Identification of Heregulin, a Specific Activator of p185erbB2”,Science, 256,1205-1210 (May 22, 1992).
Lee et al., “Assignment of heregulin (HGL) to human chromosome 8p22-p11 by PCR analysis of somatic cell hybrid DNA”Genomics, 16:790-791 (1993).
Lemke & Brockes, “Identification and purification of glial growth factor”,J. Neurosci., 4(1):75-83 (1984).
Levi et al., “The functional characteristics of Schwann Cells cultured from human peripheral nerve after transplantation into a gap within the rat sciatic nerve”,J. Neuroscience, 14(3):1309-1319 (1994).
Marchionni et al., “Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system”,Nature, 362:312-318 (1993).
Marikovsky et al., “ErbB-3 mediates differential mitogenic effects of NDF heregulin isoforms on mouse keratinocytes”,Oncogene, 10:1403-1411 (1995).
Meyer & Birchmeir, “Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development”,Proc. Natl. Acad. Sci., 91:1064-1068 (1994).
Meyer et al., “Isoform-specific expression and function of neuregulin”,Development, 124:3575-3586 (1997).
Orr-Urteger et al., “Neural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21”,Proc. Natl. Acad. Sci. USA, 90:1867-1871 (1993).
Patel et al., “Heregulin (HRG) and human epideral receptor (HER) 2 and 3 are modulated duri”,Jour. of Invest. Med., (XP002123357) 45(3):284A (1997).
Patel et al.,Am. J. Resp. Cell and Mol.e Biol., 22(4):432-440 (2000).
Peles et al., “Isolation of the Neu/HER-2 Stimulatory Ligand: A 44 Kd Glycoprotein that Induces Differentiation of Mammary Tumor Cells”,Cell, 69(1):205-216 (1992).
Pinkas-Kramarski et al.,, “Brain neurons and glial cells express Neu differentiation factor/heregulin: A survival factor for astrocytes”,Proc. Natl. Sci. USA, 91:9387-9391 (1994).
Plowman et al., “Heregulin induces tyrosine phosphorylation of HER4/p180erbB4”,Nature(Letters to Nature), 366:473-475 (Dec. 2, 1993).
Ram et al., “Mitogenic Activity of Neu Differentiation Factor/Heregulin Mimics that of Epidermal Growth Factor and Insulin-Like Growth Factor-1 in Human Mammary Epithlial Cells”,J. Cellular Physiology, 163:589-596 (1995).
Shaefer et al., “γ-Heregulin: a novel heregulin isoforms that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175”,Onogene, 15:1385-1394 (1997).
Sklar et al., “A novel growth factor for muscle-rhGGF2”,J. Cell Biochem., (abstract W462) p. 540 (1994).
Sliwkowski et al., “Coexpression of erbB2 and erbB3 Proteins Reconstitutes a High Affinity Receptor for Heregulin”,Journal of Biological Chemistry, 269(20): 14661-14665 (May 20, 1994).
Taber's Cyclopedic Medical
Kern Jeffrey A.
Sliwkowski Mark X.
Genentech Inc.
University of Iowa Research Foundation
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