Use of heregulin as a growth factor

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S399000, C435S377000

Reexamination Certificate

active

07153828

ABSTRACT:
Ligands which bind to the HER2, HER3 and/or HER4 receptors are useful as normal epithelial cell growth factors.

REFERENCES:
patent: 4935341 (1990-06-01), Bargmann et al.
patent: 4968603 (1990-11-01), Slamon et al.
patent: 5183884 (1993-02-01), Kraus et al.
patent: 5288477 (1994-02-01), Bacus et al.
patent: 5367060 (1994-11-01), Vandlen et al.
patent: 5401638 (1995-03-01), Carney et al.
patent: 5464751 (1995-11-01), Greene et al.
patent: 5578482 (1996-11-01), Lippman et al.
patent: 5686415 (1997-11-01), Carnahan et al.
patent: 5720954 (1998-02-01), Hudziak et al.
patent: 5772997 (1998-06-01), Hudziak et al.
patent: 5840525 (1998-11-01), Vandlen et al.
patent: 6015567 (2000-01-01), Hudziak et al.
patent: 6033660 (2000-03-01), Mather et al.
patent: 6096873 (2000-08-01), Schaefer et al.
patent: 6165464 (2000-12-01), Hudziak et al.
patent: 6500941 (2002-12-01), Schaefer et al.
patent: 2004/0258685 (2004-12-01), Brunetta et al.
patent: 444961 (1991-09-01), None
patent: 505148 (1992-09-01), None
patent: 0 599 274 (1994-06-01), None
patent: WO 87/07646 (1988-02-01), None
patent: WO 89/10412 (1989-11-01), None
patent: WO 91/15230 (1991-10-01), None
patent: WO 92/18627 (1992-10-01), None
patent: WO 92/20798 (1992-11-01), None
patent: WO 93/22424 (1993-11-01), None
patent: WO 94/00140 (1994-01-01), None
patent: WO 94/04560 (1994-03-01), None
patent: WO 94/08007 (1994-04-01), None
patent: WO 94/28133 (1994-08-01), None
patent: WO 94/26298 (1994-11-01), None
patent: WO 95/32724 (1995-12-01), None
patent: WO 96/15244 (1996-05-01), None
patent: WO 96/30403 (1996-10-01), None
patent: WO 98/02541 (1998-01-01), None
patent: WO 98/35036 (1998-08-01), None
Patel et al., Am. J. Respiratory Cell and Molecular Biol. vol. 22, pp. 432-440, Apr. 2000.
Crystal, RG., (JAMA, vol. 285(5): 612-618) Feb. 7, 2001.
Carraway & Cantley, “ANeuAcquaintance for ErbB3 and ErbB4: A Role for Receptor Heterodimerization in Growth Signaling.”Cell78: 5-8 (Jul. 15, 1994).
Carter et al., “Humanization of an Anti-p185\supHER2\nor Antibody for Human Cancer Therapy.”Proc. Natl. Acad. Sci. USA89: 4285-4289 (May 1992).
Carter et al., “Towards an Immunotherapy for p185\supHER2\nor Overexpression Tumors.”Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment, R.L. Ceriani, ed., New York: Plenum Press pp. 83-94 (1994).
Cole et al., “The EBV-Hybridoma Technique and its Application to Human Lung Cancer.”Monoclonal Antibodies and Cancer Therapy, New York: Alan R. Liss, Inc. pp. 77-96 (1985).
Dillman, R., “Antibodies as Cytotoxic Therapy.”J. Clin. Oncol.12(7): 1497-1515 (Jul. 1994).
Drebin et al., “Development of Monoclonal Antibodies Reactive with the Product of the neu Oncogene.”Symposium on Fundamental Cancer Research38: 277-289 (1986).
Sato et al., “Biological Effects in vitro of Monoclonal Antibodies to Human Epidermal Growth Factor Receptors.”Mol. Biol. Med.1: 511-529 (1983).
Taetle et al., “Effects of Anti-Epidermal Growth Factor (EGF) Receptor Antibodies and an Anti-EGF Receptor Recombinant-Ricin A Chain Immunoconjugate on Growth of Human Cells.”J. Natl. Cancer Inst.80(13): 1053-1059 (1988).
Patel, N.V. et al., “Heregulin (HRG) and human epideral receptor (HER) 2 and 3 are modulated duringin vitrohuman lung growth and differentiation,”Jour. of Invest. Med., (XP-002113357), vol. 45, No. 3, pp. 284A (1997).
Brockes et al , “Glial growth factor-like activity in Schwann Cell tumors”,Annals of Neurology, 20:317-322 (1986).
Brockes et al , “Purification and preliminary characterization of a glial growth factor from the bovine pituitary”,Journal of Biological Chemistry, 255(18):8374-8377 (1980).
Brockes et al , “Assay and isolation of glial growth factor from the bovine pituitary”,Methods in Enzymology, 147:217-223 (1987).
Carraway et al., “The erbB3 gene product is a receptor for heregulin”,Journal of Biological Chemistry, 269(19):14303-14306 (1994).
Corfas & Fischback, “The number of Na+ channels in cultured chick muscle is increased by ARIA, an acetylcholine receptor-inducing activity”,J. Neuroscience, 13(5):2118-2125 (1993).
Danilenko et al., “Neu differentiation factor (NDF) accelerates epidermal migration and differentiation in excisional wounds”FASEB, 8(4-5):abst. no. 3101, p. A535 (1994).
Danilenko et al, “Neu Differentiation Factor Upregulates Epidermal Migration and Integrin Expression in Excisional Wounds”,Journal of Clinical Investigation, 95(2):842-851 (1995).
Falls et al., “ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the Neu ligand family”,Cell, 72:801-815 (1993).
Fendly et al., “Characterization of Murine Monoclonal Antibodies Reactive to Either the Human Epidermal Growth Factor Receptor or HER2
eu Gene Product”,Cancer Research, 50:1550-1558 (Mar. 1, 1990).
Ho, W. et al., “Sensory and Motor Neuron-derived Factor”Journal of Biological Chemistry, 270(24):14523-14532 (Jun. 16, 1995).
Holmes et al., “Identification of Heregulin, a Specific Activator of p185erbB2”,Science, 256,1205-1210 (May 22, 1992).
Lee et al., “Assignment of heregulin (HGL) to human chromosome 8p22-p11 by PCR analysis of somatic cell hybrid DNA”Genomics, 16:790-791 (1993).
Lemke & Brockes, “Identification and purification of glial growth factor”,J. Neurosci., 4(1):75-83 (1984).
Levi et al., “The functional characteristics of Schwann Cells cultured from human peripheral nerve after transplantation into a gap within the rat sciatic nerve”,J. Neuroscience, 14(3):1309-1319 (1994).
Marchionni et al., “Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system”,Nature, 362:312-318 (1993).
Marikovsky et al., “ErbB-3 mediates differential mitogenic effects of NDF heregulin isoforms on mouse keratinocytes”,Oncogene, 10:1403-1411 (1995).
Meyer & Birchmeir, “Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development”,Proc. Natl. Acad. Sci., 91:1064-1068 (1994).
Meyer et al., “Isoform-specific expression and function of neuregulin”,Development, 124:3575-3586 (1997).
Orr-Urteger et al., “Neural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21”,Proc. Natl. Acad. Sci. USA, 90:1867-1871 (1993).
Patel et al., “Heregulin (HRG) and human epideral receptor (HER) 2 and 3 are modulated duri”,Jour. of Invest. Med., (XP002123357) 45(3):284A (1997).
Patel et al.,Am. J. Resp. Cell and Mol.e Biol., 22(4):432-440 (2000).
Peles et al., “Isolation of the Neu/HER-2 Stimulatory Ligand: A 44 Kd Glycoprotein that Induces Differentiation of Mammary Tumor Cells”,Cell, 69(1):205-216 (1992).
Pinkas-Kramarski et al.,, “Brain neurons and glial cells express Neu differentiation factor/heregulin: A survival factor for astrocytes”,Proc. Natl. Sci. USA, 91:9387-9391 (1994).
Plowman et al., “Heregulin induces tyrosine phosphorylation of HER4/p180erbB4”,Nature(Letters to Nature), 366:473-475 (Dec. 2, 1993).
Ram et al., “Mitogenic Activity of Neu Differentiation Factor/Heregulin Mimics that of Epidermal Growth Factor and Insulin-Like Growth Factor-1 in Human Mammary Epithlial Cells”,J. Cellular Physiology, 163:589-596 (1995).
Shaefer et al., “γ-Heregulin: a novel heregulin isoforms that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175”,Onogene, 15:1385-1394 (1997).
Sklar et al., “A novel growth factor for muscle-rhGGF2”,J. Cell Biochem., (abstract W462) p. 540 (1994).
Sliwkowski et al., “Coexpression of erbB2 and erbB3 Proteins Reconstitutes a High Affinity Receptor for Heregulin”,Journal of Biological Chemistry, 269(20): 14661-14665 (May 20, 1994).
Taber's Cyclopedic Medical

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of heregulin as a growth factor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of heregulin as a growth factor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of heregulin as a growth factor will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3677588

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.