Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1993-03-05
1994-03-15
Rose, Shep
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
424 49, 424 54, A61K 716, A61K 718, A61K 722
Patent
active
052944336
ABSTRACT:
The subject invention relates to methods for prevention or treatment of gingivitis or periodontitis comprising topical administration, to gingival tissues of the oral cavity, of a composition comprising a safe and effective amount of a selective histamine-2 receptor antagonist compound, and oral care compositions used therefore.
REFERENCES:
patent: 3574859 (1971-04-01), Kosti
patent: 3822349 (1974-07-01), Kosti
patent: 3832460 (1974-08-01), Kosti
patent: 3839522 (1974-10-01), Kosti
patent: 3950333 (1976-04-01), Durant et al.
patent: 4128658 (1978-12-01), Price et al.
patent: 4256743 (1981-03-01), Goldhaber
patent: 4283408 (1981-08-01), Hirata et al.
patent: 4293557 (1981-10-01), Shibata et al.
patent: 4375547 (1983-03-01), Pioch
patent: 4386099 (1983-05-01), Cereda et al.
patent: 4419352 (1983-12-01), Cox et al.
patent: 4569837 (1986-02-01), Suzuki et al.
patent: 4572832 (1986-02-01), Kigasawa et al.
patent: 4585790 (1986-04-01), Padfield et al.
patent: 4933182 (1990-06-01), Higashi et al.
patent: 4952402 (1990-08-01), Sparks et al.
patent: 5023082 (1991-06-01), Friedman et al.
patent: 5053032 (1991-10-01), Barclay et al.
patent: 5102666 (1992-04-01), Acharya
patent: 5110605 (1992-05-01), Acharya
patent: 5188839 (1993-02-01), Pearmain
patent: 5200194 (1993-04-01), Edgren et al.
patent: 5200195 (1993-04-01), Dong et al.
patent: 5221688 (1993-06-01), Clitherow et al.
Ash; A. S. F. & H. O. Schild, "Receptors mediatiing Some Actions of Histamine", Brit. J. Pharmacol. Chemother., vol. 27 (1966), pp. 427-439.
Black, J. W., W. A. M. Duncan, C. J. Durant, C. R. Ganellin & E. M. Parsons, "Definition and Antagonism of Histamine H.sub.2 -Receptors", Nature, vol. 236 (Apr. 21, 1972), pp. 385-390.
Dews, P. B. & J. D. P. Graham, "The Antihistamine Substance 2786 R.P.", Brit. J. Pharmacol., vol. 1 (1946); p. 278.
Loew, E. R. & O. Chickering, "Gastric Secretion in Dogs Treated with Histamine Antagonist, Thymoxyethyldiethylamine", Proc. Soc. Exp. Biol. and Med., vol. 48 (1941), pp. 65-68.
Nakamoto, T., M. McCroskey & H. M. Mallek, "The Role of Ascorbic Acid Deficiency in Human Gingivitis-A New Hypothesis", J. Theor. Biol., vol. 108 (1984), pp. 163-171.
Pernsteiner, C. L. & M. M. Ash, "Effect of Topical Application of Phenylephrine Hydrochloride on Hyperplastic Gingivitis", J. Peridontol., vol. 48 (1977), pp. 473-477.
Trendelenburg, U., "The Action of Histamine and 5-Hydroxytryptamine on Isolated Mammalian Atria", J. Pharmacol. & Exp. Ther., vol. 130 (1960), pp. 450-460.
Ebel James P.
Singer Robert E.
Crosmun Jean R.
Graff IV Milton B.
Rose Shep
Suter David L.
The Procter & Gamble & Company
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