Use of growth factor IGF-I and/or IGF-II

Details Use of growth factor IGF-I and/or IGF-II Use of growth factor IGF-I and/or IGF-II

1996-03-07

1998-01-20

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, 530303, 530309, C07K 710, A61K 3800, A61K 3736

Patent

active

057101272

ABSTRACT:
The present invention relates to a composition comprising exogenous human or animal IGF-I or IGF-II or both or effective analogs thereof comprising foodstuff for oral administration wherein the foodstuff is selected from the group consisting of artificial milk, natural milk and colostrum.

REFERENCES:
patent: 5482926 (1996-01-01), Gluckman et al.
patent: 5534493 (1996-07-01), Gluckman et al.
Heinz-Erian et al., Identification and In Situ Localization of the Insulin-Like Growth Factor II, Endocrinology (1991), p. 1769.
Schober et al., Endocrinology, vol. 126, No. 2, (1990), pp. 1125-1132.
Young et al., Insulin-Like Growth Factors and the Developing and Mature Rat Small Intestine: Receptors and Biological Actions, Digestion, 1990 (46), pp. 240-252.
Rivard et al., Negative Control by Sandostatin on Pancreatic and Duodenal Growth: A Possible Implication of Insulin-Like Growth Factor I, Regulatory Peptides (1991), vol. 34, pp. 13-23.
Grey et al., Insulin-Like Growth Factor II/Mannose-6-Phosphate Receptors Are Transiently Increased in the Rat Distal Intestinal Epithelium After Resection, Molecular and Cellular Endocrinology (1991), vol. 75, pp. 221-227.
Moessner et al., Chem. Abstract 108 (1988), 69411a.
Williams et al., Chem. Abstract 100 (1984), 133010h.
Koenuma et al., Insulin and Insulin-Like Growth Factor I Stimulate Proliferation of Metastatic Variants of Colon Carcinoma 26, Japan J. Cancer Res. 1989, Jan., vol. 80, No. 1, pp. 51-58 (Abstract).
Culouscou, Purification of a Colon Cancer Cell Growth Inhibitor and its Identification as an Insulin-Like Growth Factor Binding Protein, Cancer-Ref. (1991), Jun., Vol. 51, No. 11, pp. 2813-2819 (Abstract).

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