Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-08-01
2006-08-01
Peselev, Elli (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
Reexamination Certificate
active
07084122
ABSTRACT:
Glycosides of diacylglycerol, e.g. 3-β-D-galactopyranosyloxy-2-(octadeca-9Z,12Z,15Z-trienoyloxy)propanyl octadeca-9Z,12Z,15Z-trienoate (GOPO), which was isolated from extracts of rose-hips by activity guided fractionation, can be used as an oral anti-inflammatory agent for the treatment of inflammatory diseases such as arthritis and osteoarthrosis.
REFERENCES:
patent: 5486536 (1996-01-01), Ward et al.
patent: 5620962 (1997-04-01), Winget
patent: 5767095 (1998-06-01), Winget
patent: 6024960 (2000-02-01), Kharazmi et al.
patent: 19634019 (1998-02-01), None
patent: 19634021 (1998-02-01), None
patent: 0671406 (1995-09-01), None
patent: 0671407 (1995-09-01), None
patent: 0671407 (1995-09-01), None
patent: 05-271270 (1993-10-01), None
patent: 06-336437 (1994-12-01), None
patent: 07-149786 (1995-06-01), None
patent: 94/24984 (1994-11-01), None
patent: 98/30573 (1998-07-01), None
English language translation of DE 196 34 019, published Feb. 26, 1998.
Nagatsu, Akito et al., “Synthesis and Structure—Anti-Tumor-Promoting Activity relationship of Mongalactosyl Diacylglycerols”,Bioorganic&Medicinal Chemistry(1994), vol. 4, No. 13, pp. 1619-1622.
Erdem Yesilada et al., “Inhibitory effects of Turkish folk remedies on inflammatory cytokines: interleukin- 1α, interleukin-1β and tumor necrosis factor α,” Journal of Ethnopharmacology 58, (1997), 59-73.
Tiwalade A. Olugbade et al., “Prieurianoside, a protolimonoid glucoside from the leaves ofTrichilia prieuriana,” Phytochemistry 54, (2000) 867-870.
International Search Report for Application No. PCT/DK02/00783, dated Apr. 23, 2003.
Naoki Ohta et al., “Synthesis of biologically active galactosyl and glucosyl-glycerol derivatives,” Chem. Pharm. Bull. 39(5) 1337-1339 (1991).
Hirotaka Shibuya et al., “Syntheses of a Glycerophospholipid, C16-Platelet Activating Factor and a Palmitoyl Analogue of M-5 an Anti-inflammatory Glyceroglycolipid1.” Chem. Pharm. Bull. 40(5) 1166-1169 (1992).
Cateni, F1et al., Biologically active compounds from Euphorbiaceae; Three new glycolipids with anti-inflammatory activity fromEuphobia cyparissiasL., Pharm. Pharmacol Lett (2001) 2: 53-57.
Chul Kim et al., “Galactolipids from mori folium and their hypoglycemic effect,” Saengyak Hakhoechi (2000), 31(1), 95-100, ABSTRACT.
Nobutoshi Murakami et al., “An autolytic substance in a freshwater cyanobacterium phormidium tenue,” Chem. Pharm. Bull. 38(3), pp. 812-814 (1990).
Nobutoshi Murakami et al., “Seven new monogalactosyl diacylglycerols isolated from the axenic cyanobacterium phormidium tenue1,” Chem. Pharm. Bull. 38(2), pp. 3497-3499, (1990).
Takashi Morimoto et al., “Anti-tumor-promoting glyceroglycolipids from the green alga, chlorella vlgaris,” Phytochemistry vol. 40, No. 5, pp. 1433-1437, (1995).
Hideaki Shirahashi et al., “Isolation and identification of anti-tumor-promoting principles from the fresh water cyanobacterium phomidium tenue1,” Chem. Pharm. Bull. 41(9), pp. 1664-1666 (1993).
J. Jakupovic et al., Millerenolides, sesquiterpene lactones from millenia quinqueflora, Phytochemistry, vol. 26, No. 7, pp. 2011-2017, 1987.
Putul Baruah et al., “A monoacyl galactosylglycerol from sonchus arvensis,” Phytochemistry, vol. 22, No. 8, pp. 1741-1744, 1983.
Akira Murakami et al., “Glyceroglycolipids from citrus hystrix, a traditional herb in Thailand, potently inhibit the tumor-promoting activity of 12-O-Tetradecanoylphorbol 13-Acetate in mouse skin,” J. Agric. Food Chem. 1995, 43, pp. 2779-2783.
K. Winther et al., “The anti-inflammatory properties of rose-hip,” Inflammopharmacology, vol. 7, No. 1, pp. 63-68, (1999).
Hirotaka Shibuya et al., “Syntheses of a glycerophospholipid, c16-platelet activating factor and a palmitoyl analogue of an anti-inflammatory glyceroglycolopid1,” Chem. Pharm. Bull. 40(5), pp. 1166-1169 (1992.
Naoki Ohta et al., “Synthesis of biologically active galactosyl and glucosyl-glycerol derivatives,” Chem. Pharm. Bull. 39(5), pp. 1337-1339 (1991.
Hiroyuki Kikuchi et al., “Foliaspongin, an antiinflammatory bishomosesterterpene from the marine sponge phyllospongia foliascens (Pallas).” Chem. Pharm. Bull. 29(5), pp. 1492-1494 (1981).
Hiroyuki Kikuchi et al., “Marine natural products. X1. Pharmacologically active glycolipids from the Okinawan Marine sponge phyllospongia foliascens (Pallas),” Chem. Pharm. Bull. 30(10), pp. 3544-3547 (1982).
Armandodoriano Bianco et al., “Microcomponents of olive oil. Part II: Digalactosyldiacylglycerols from Olea europea,” Food Chemistry, vol. 62, No. 3, pp. 343-346, (1998).
Jee H. Jung et al., “Diacylglycerylgalactosides from arisaema amurense,” Phytochemistry, vol. 42, No. 2, pp. 447-452, 1996.
Ryo Yamauchi et al., “Analysis of molecular species of glycolipids in fruit pastes of red bell pepper (capsicum annuum L.) by high-performance liquid chromatography-mass spectrometry,” J. Agric. Food Chem. (2001), 49, pp. 622-627.
Rene Suhr et al., “Synthesis of glycosyl glycerols and related glycolipids,” J. Carbohydrate Chemistry, 17(6), pp. 937-968 (1998).
X.-M. Wang et al., “Comparison of fatty acid composition in tissues of low linolenate mutants of soybean,” Phytochemistry, vol. 28, No. 2, pp. 411-414, (1989).
Isao Kitagawa et al., Saponin and Sapogenol. XLVI.1On the constituents in aerial part of American Alfalfa, Medicago sativa L. The structure of dehydrosoyasaponin I, Yakugaku Zasshi, 108(6), pp. 547-554 (1988).
Nobutoshi Murakami et al., “Studies on glycolipids. III.1Glyceroglycolipids from an axenically cultured cyanobacterium phormidium tenue,” Chem. Pharm. Bull. 39(9), pp. 2277-2281 (1991).
Christian Wegner et al., “Tensioactive compounds from the aquatic plant ranunculus fluitans L. (Ranunculaceae),” Helvetica Chimica Acta, vol. 83, pp. 1454-1464, (2000).
Naoki Ohta et al., “Synthesis of biologically active galactosyl and glucosy-glycerol derivates,” Chem. Pharm. Bull. 39(5), pp. 1337-1339, (1991).
Arsalan Kharazmi et al., “Rose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivo,” Inflammopharmocology, vol. 7, No. 4, pp. 377-386 (1999).
Peter Libby, “Atherosclerosis: The new view,” Scientific American, May 2002, pp. 29-37.
T. Ringbom, et al., “COX-2 Inhibitory effects of naturally occuring and modified fatty acids,” J. Nat. Prod. 2001, 64, pp. 745-749.
Hiroyuki Kikuchi et al., “Marine natural products. XI.1Antiinflammatory scalarane-type bishomosestertterpene foliaspongin, from the Okinawan Marine sponge phyllospongia foliascens (Pallas),” Chem. Pharm. Bull. 31(2), pp. 552-556 (1983).
Brandt Kirsten
Christensen Lars Porskjær
Christensen Søren Brøgger
Kharazmi Arsalan
Larsen Erik
Hunton & Williams
Peselev Elli
LandOfFree
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