Use of glucose-6-phosphate isomerase and antibodies thereto...

Details Use of glucose-6-phosphate isomerase and antibodies thereto... Use of glucose-6-phosphate isomerase and antibodies thereto...

2006-02-24

2010-02-16

Haddad, Maher M (Department: 1644)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S139100, C424S158100, C800S003000, C800S004000, C800S005000, C800S006000

Reexamination Certificate

active

07662375

ABSTRACT:
The present invention relates to the use of antibodies against glucose-6-phosphate isomerase (GPI) and like protein for diagnosis of arthritis and the use of said protein for treatment of arthritis. It is also aimed at a process for isolating monoclonal antibodies capable of transferring arthritis and antibodies thereof, as well as a method for determining the anti-arthritis potential of a composition.

REFERENCES:
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Lederman et al. ‘A single amino acid substitution in a common African allele of the CD4 molecule ablates binding of the monoclonal antibody, OKT4.’ Molec. lmmunol. 28:1171-1181, 1991.
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