Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1998-03-05
1999-12-21
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530308, 530324, A61K 3800, A61K 3826
Patent
active
060049324
ABSTRACT:
The use of glucagon as a metabolic conditioner for dairy cows and other ruminants is described. The glucagon is preferably administered in an amount of from 1-10 mg per day, preferably during the time period beginning 7 days before calving and continuing until 21 days after calving. The administration of glucagon decreases the incidence of metabolic diseases and metabolic imbalances associated with fatty liver, allows cows to reach peak mile production sooner, and results in increased feed intake during the early stages of lactation.
REFERENCES:
patent: 4369172 (1983-01-01), Schor et al.
patent: 5143902 (1992-09-01), Merrifield et al.
patent: 5597797 (1997-01-01), Clark
Brockman, R.P., "Roles for Insulin and Glucagon in the Development of Ruminant Ketosis--A Review" Can. Vet. J., 1976, 20, 121-126.
Wright, et al., "Glucagon (1-6) binds to Glucagon Receptor and Activates Hepatic Adenylate Cyclase" J. Biol. Chem., 1979, 254 (2), 268.
Baird, G.D., "Primary Ketosis in the High-Producing Dairy Cow: Clinical and Subclinical Disorders, Treatment, Prevention, and Outlook" J. Dairy Sci., 1982, 65, 1-10.
Drackley, et al., "Metabolic Responses of Lactating Goats to Feed Restriction and Dietary 1.3-Butanediol." J. Dairy Sci., 1989, 72, 3204.
Bauman, D.E., "Intermediary Metabolism of Adipose Tissue" Fed. Proc., 1976, 35 (11), 2308.
Herdt, T.H., et al., "Hepatic Triacylglycerol Synthesis During a Period of Fatty Liver Development in Sheep" J. Anim. Sci., 1988, 66, 1997-2013.
Gerloff, B.J., et al., "Inositol and Hepatic Lipidosis. Effect of Inositol Supplementation and Time From Partrition on Liver and Serum LIpids in Dairy Cows" J. Anim. Sci., 1986, 62, 1682-1692.
Malinovska, V., et al., "The Therapeutic Effect of Glucagon Chelaton III on the Arterial Wall after Experimental Lipidosis and Calcification" Chem. Abst. 1984:35342, 1983.
Brockman, R.P., "Roles for Insulin Glucagon in the Development of Ruminant Ketosis (Review)", Can. Vet. J., 1979, 20, 121.
Brockman, R.P., "Effects of Glucagon and Insulin on Lipolysis and Ketogensis in Sheep" Ca. J. Comp. Med., 1976, 40, 166.
Beitz Donald C.
Hippen Arnold R.
Young Jerry W.
Iowa State University & Research Foundation, Inc.
Jameison Fabian A.
Tsang Cecilia J.
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