Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-05-09
1991-03-26
Rollins, John W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549297, 4241951, 435 1, A61K 3134
Patent
active
050029657
ABSTRACT:
A living tissue or living cell preservation solution comprising an effective amount of a ginkgolide to reduce reperfusion injury in living tissue which has been stored therein and a substance or mixture or substances present in an amount sufficient to produce an osmotic pressure in said solution approximately equal to the osmotic pressure or mammalian cell and a method for preventing or reducing reperfusion injury in transplanted mammalian organs, which comprises contacting an organ prior to reperfusion with an effective amount of a ginkgolide to reduce reperfusion injury in said organ.
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Foegh et al., "PAF and BN 52021 in Organ Transplant Rejection", Ginkgolides-Chemistry, Biology, Pharmacology and Clinical Perspectives, vol. 1, edited by P. Braquet, J. R. Prous Science Publishers, pp. 743-748 (May 1, 1988).
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Foegh Marie L.
Ramwell Peter W.
Rollins John W.
Societe de Conseils de Recherches et d'Applications Scientifique
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