Use of Ginkgo extract

Details Use of Ginkgo extract Use of Ginkgo extract

2006-07-18

2006-07-18

Kishore, Gollamudi S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S461000, C514S473000, C424S714000

Reexamination Certificate

active

07078434

ABSTRACT:
The present invention is directed to the use of the extract ofGinkgo bilobaleaves or isolated Ginkgolide B (GKB), a component of the extract ofGinkgo bilobaleaves in a method for decreasing the expression of peripheral-type benzodiazepine receptor (PBR) in cells of a patient in need thereof. Further, the present invention is directed to the use of the extract ofGinkgo bilobaleaves or isolated GKB in a method for decreasing the proliferation of cancer cells in a patient. More particularly, the present invention is directed to the use of the extract ofGinkgo bilobaleaves or isolated GKB in a method of decreasing cancer cell proliferation in a patient wherein the cancer cell is human breast cancer cell. Even more particularly, the present invention is directed to the use of the extract ofGinkgo bilobaleaves or isolated GKB in method of decreasing cancer cell proliferation in a patient wherein the cancer cell is of the aggressive and invasive phenotype and expresses high levels of PBR in comparison to non-aggressive cancer cell.

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