Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-09-06
2008-12-16
Rao, Deepak (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S483000, C548S484000
Reexamination Certificate
active
07465750
ABSTRACT:
This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety. This invention also provides a method of treating depression and/or anxiety in a subject which comprises administering to the subject a composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a GAL3 receptor antagonist.
REFERENCES:
patent: 4874687 (1989-10-01), Itabashi et al.
patent: 4921503 (1990-05-01), Anderson et al.
patent: 4946956 (1990-08-01), Wheeler et al.
patent: 5017466 (1991-05-01), Kobayashi et al.
patent: 5198461 (1993-03-01), Watjen et al.
patent: 5547949 (1996-08-01), Maho et al.
patent: 5728704 (1998-03-01), Mylari et al.
patent: 5801150 (1998-09-01), Caillot et al.
patent: 5840893 (1998-11-01), Bukrinsky et al.
patent: 6287788 (2001-09-01), Bard et al.
patent: 6329197 (2001-12-01), Bard et al.
patent: 6368812 (2002-04-01), Bard et al.
patent: 7081470 (2006-07-01), Konkel et al.
patent: 7166635 (2007-01-01), Konkel et al.
patent: 7220775 (2007-05-01), Blackburn
patent: 2003/0027254 (2003-02-01), Bard et al.
patent: 2003/0118096 (2003-06-01), Bard et al.
patent: 0359465 (1990-03-01), None
patent: 0363002 (1990-04-01), None
patent: 0640599 (1995-03-01), None
patent: 0667340 (1995-08-01), None
patent: 0788890 (1997-08-01), None
patent: 0945442 (1999-09-01), None
patent: 0972770 (2000-01-01), None
patent: 1477349 (1977-06-01), None
patent: 11158073 (1977-06-01), None
patent: 075449 (2002-03-01), None
patent: WO9325539 (1993-12-01), None
patent: WO9815570 (1998-04-01), None
patent: WO9941253 (1999-08-01), None
patent: WO9950250 (1999-10-01), None
patent: WO9965875 (1999-12-01), None
patent: WO002865 (2000-01-01), None
El-Ezbawy et al., Caplus Abstract 112:178540, 1990.
Hokfelt, T. et al., “Galanin and NPY, Two Peptides with Multiple Putative Roles in the Nervous System”, Horm. Metab. res. (1999);31:330-334.
Razani, H. et al., Intraventricular Galanin Produces a Time-Dependent Modulation of 5-HT1A in the Dorsal Raphe of the Rat:, Neuropharmacology and Neurotoxicology (2000) 11(18):3943-3948.
U.S. Serial No. 10/214,873 (Konkel et al.), filed Aug. 7, 2002.
U.S. Serial No. 10/066,175, filed Jan. 31, 2002.
Bionet Research Ltd., catalog #11L-312S(1-Phenyl-3-{[3-(trifluoromethyl)phenyl]limino}-1,3-dihydro-2H-indol-2-on3).
U.S. Serial No. 10/006,343,, filed Dec. 3, 2001.
U.S. Serial No. 10/007,132, filed Dec. 3, 2001.
Chemical Abstracts Registry No. 61038-64-0, 2002.
Chemical Abstracts Registry No. 41230-77-7, 2002.
Chemical Abstracts Registry No. 130186-15-1, 2002.
Chemical Abstracts Registry No. 130186-16-2, 2002.
Chemical Abstracts Registry No. 130186-17-3, 2002
Chemical Abstracts Registry No. 130186-18-4, 2002.
Chemical Abstracts Registry No. 130186-21-9, 2002.
Chemical Abstracts Registry No. 130270-13-2, 2002.
Chemical Abstracts Registry No. 133939-75-0, 2002.
Chemical Abstracts Registry No. 56984-58-8, 2002.
Chemical Abstracts Registry No. 77910-42-0, 2002.
Chemical Abstracts Registry No. 70010-41-2, 2002.
Chemical Abstracts Registry No. 189264-35-5, 2002.
Chemical Abstracts Registry No. 88291-04-7, 2002.
Chemical Abstracts Registry No. 88291-07-0, 2002.
Chemical Abstracts Registry No. 154118-05-5, 2002.
Chemical Abstracts Registry No. 155717-81-0, 2002.
Chemical Abstracts Registry No. 155717-82-1, 2002.
Chemical Abstracts Registry No. 159967-24-5, 2002.
Chemical Abstracts Registry No. 138601-94-2, 2002.
Chemical Abstracts Registry No. 136647-69-3, 2002.
Chemical Abstracts Registry No. 136647-72-8, 2002.
Chemical Abstracts Registry No. 77297-28-0, 2002.
Chemical Abstracts Registry No. 43002-26-2, 2002.
Chemical Abstracts Registry No. 303984-69-2, 2002.
Chemical Abstracts Registry No. 122725-53-5, 2002.
Chemical Abstracts Registry No. 122803-89-8, 2002.
Chemical Abstracts Registry No. 303149-10-2, 2002.
Chemical Abstracts Registry No. 303149-08-8, 2002.
Chemical Abstracts Registry No. 303149-06-6, 2002.
Chemical Abstracts Registry No. 303984-47-6, 2002.
Chemical Abstracts Registry No. 303149-14-6, 2002.
Chemical Abstracts Registry No. 303149-12-4, 2002.
Chemical Abstracts Registry No. 303984-51-2, 2002.
Chemical Abstracts Registry No. 303984-49-8, 2002.
Chemical Abstracts Registry No. 303984-48-7, 2002.
Chemical Abstracts Registry No. 303984-52-3, 2002.
Chemical Abstracts Registry No. 303984-60-3, 2002.
Chemical Abstracts Registry No. 303984-61-4, 2002.
Chemical Abstracts Registry No. 303984-62-5, 2002.
Chemical Abstracts Registry No. 33984-68-1, 2002.
English Language Abstract for Japanese Patent No. JP 11158073, 1977.
Blackburn Thomas P.
Boteju Lakmal W.
Chen Heidi
Jimenez Hermo
Konkel Michael J.
H. Lundbeck A/S
Pelto Don J.
Rao Deepak
Sheppard Mullin Richter & Hampton LLP
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