Use of Fosfluridine Tidoxil (FT) for the treatment of...

Details Use of Fosfluridine Tidoxil (FT) for the treatment of... Use of Fosfluridine Tidoxil (FT) for the treatment of...

2008-05-27

2008-05-27

Lewis, Patrick T (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S043000, C514S045000, C514S047000, C514S049000, C514S050000, C514S051000, C514S885000, C514S908000, C536S026700, C536S026800

Reexamination Certificate

active

07378401

ABSTRACT:
The present invention is directed to the systemic administration of Fosfluridine Tidoxil, (5-fluorouridine)-5′-phosphoric acid (3-dodecylmercapto-2-decyloxy)propylester or a salt thereof, for the treatment of intraepithelial proliferative diseases such as actinic keratosis. The Fosfluridine Tidoxil can be systemically administered alone or in combination with topical treatment agents.

REFERENCES:
patent: 6025343 (2000-02-01), Herrmann et al.
patent: 2005/0090659 (2005-04-01), Herrmann
patent: 1 229 040 (2002-08-01), None
Anonymous, “Phase II study intitiated with oral fosfluridine in actinic keratosis” [Online], Aug. 16, 2005, Retrieved from Internet: URL: www.bioportfolio.com/aug—05/17—08—2005.
Joseph L. Jorizzo, “Current and Novel Treatment Options for Actinic Keratosis”, Incorporating Medical and Surgical Dermatology, vol. 8, No. 3, Dec. 1, 2004, pp. 13-21.
Heidelberg Pharma AG, “Fosfluridine Tidoxil shows effectivness in Actinic Keratosis”, [Online] May 17, 2007, Retrieved from Internet: www.heidelberg-pharma.com
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