Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-02-10
1995-03-21
Henley, III, Raymond J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514413, 514456, 514570, 514922, 514925, 514926, 514927, 424 10, A61K 3138, A61K 3135, A61K 3119, A61K 3140, A61K 4900
Patent
active
053995848
ABSTRACT:
The subject invention relates to methods for preventing or treating damage to the mucosal lining of the gastrointestinal tract of a human or lower animal by administering a safe and effective amount of a compound having the structure: ##STR1## wherein X and Y are each independently selected from O and S; R.sup.1, R.sup.2 and R.sup.3 are each independently selected from hydrogen, hydroxy, halo, unsubstituted or monosubstituted straight or branched C.sub.1 -C.sub.4 alkanyl, and unsubstituted or substituted straight or branched C.sub.1 -C.sub.4 alkanoxy; and each of R.sup.4, R.sup.5, R.sup.6 and R.sup.7 is hydrogen or, if one or more of R.sup.1, R.sup.2 and R.sup.3 is other than hydrogen, each of R.sup.4, R.sup.5, R.sup.6 and R.sup.7 is selected from hydrogen, halo, trifluoromethyl, and unsubstituted straight or branched C.sub.1 -C.sub.4 alkanyl.
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Tariq, M., N. S. Parmar, A.
Ares Jeffrey J.
Kakodkar Sunil V.
Kelm Gary R.
Murray Peter D.
Randall Jared L.
Graff IV Milton B.
Henley III Raymond J.
Rasser Jacobus C.
Suter David L.
The Procter & Gamble & Company
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