Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution...
Reexamination Certificate
2002-09-16
2008-08-19
Hoffman, Susan C (Department: 1655)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
Reexamination Certificate
active
07413754
ABSTRACT:
The present invention relates to extracts fromCimicifugaspecies and particularly fromCimicifuga racemosa, which are suited for producing a ready-formulated drug for the selective treatment and/or prophylaxis of sexual hormone-related disorders of the uro-genital tract. The extracts in accordance with the invention are moreover suited for the treatment and/or prophylaxis of post-menopausal urinary bladder infections. They are furthermore indicated for the treatment of benign and malignant prostate hyperplasies.
REFERENCES:
patent: 5382430 (1995-01-01), Soma et al.
patent: 5411733 (1995-05-01), Hozumi et al.
patent: 5569459 (1996-10-01), Shlyankevich
patent: 5716646 (1998-02-01), Smith et al.
patent: 5795574 (1998-08-01), Breton et al.
patent: 5916565 (1999-06-01), Rose et al.
patent: 5952374 (1999-09-01), Clarkson, Jr. et al.
patent: 6008208 (1999-12-01), Petrie et al.
patent: 6242012 (2001-06-01), Newmark et al.
patent: 6267994 (2001-07-01), Nesselhut
patent: 6326366 (2001-12-01), Potter et al.
patent: 6471997 (2002-10-01), Breton et al.
patent: 2001/0025059 (2001-09-01), Kastke
patent: 2002/0010141 (2002-01-01), Ingram
patent: 2002/0172732 (2002-11-01), Ter Laak et al.
patent: 1090498 (1994-08-01), None
patent: 1158261 (1997-09-01), None
patent: 1159340 (1997-09-01), None
patent: 11158261 (1997-09-01), None
patent: 361762 (1992-06-01), None
patent: 0847755 (1997-11-01), None
patent: 204 197 (1991-12-01), None
patent: 63030417 (1988-02-01), None
patent: 63030417 (1988-09-01), None
patent: 07138179 (1995-05-01), None
patent: 07138181 (1995-05-01), None
patent: 07138181 (1995-05-01), None
patent: 09030977 (1997-02-01), None
patent: 09-124499 (1997-05-01), None
patent: 09-0301884 (1997-11-01), None
patent: 10-007580 (1998-01-01), None
patent: 10-084923 (1998-04-01), None
patent: WO 97/09056 (1997-03-01), None
patent: 9715398 (1997-05-01), None
patent: WO 99/47419 (1999-09-01), None
patent: WO 01/74345 (2001-10-01), None
patent: WO 02/36140 (2002-05-01), None
patent: WO 02/007321 (2002-09-01), None
Gura; Science (1997), vol. 278, pp. 1041-1042.
Milewicz, A., et al, “Vitex agnus castus-Extrakt zur Behandlung von Regeltempoanomalien infolge latenter Hyperprolaktinamie,” Arzneimittel Forsch 43: 752-756 (1993 (in German).
Hoberg, E., et al., “Diterpenoids from the Fruits of Vitex agnus-castus,” Phytochemistry 52: 1555-1558 (1999).
Gorkow, “Klinischer Denntnisstand von Agni-casti fructus,” Z. Phytotherapie 20: 159-168 (in German), 1999.
Einer-Jensen, N., et al., “Cimicifugaand Melbrosia Lack Oestrogenic Effects in Mice and Rats,” Maturitas 25: 149-153 (1996).
Rote Liste 1986 (Editio Cantor, Aulendorf, Wurttemburg).
Esaki, S., “Pharmacological Studies of Tectoridin and Tectorigenin,” Nippon Yakurigaku Zasshi 64: 186-198 (1968).
Petersen, F.J., Materia Medica and Clinical Therapeutics, “Cimicifuga racemosa,” 1905.
Li, J.X., et al, “Effects of Cimicifugae Rhizoma on Serum Calcium and Phosphate Levels in Low Calcium Dietary Rat . . . ,” Phytomedicine 3:379-385 (1996/97).
Duker, E.-M., et al., “Die Wirking von Extrakten ausCimicifuga racemosaauf die Gonadotropinfreizetzung in Menopausalen Frauen und . . . ”, Planta Med. 57:420-424 (1991).
Sorrentino, L. and Genazzanai. E., “Vascular Action of Acteina: Active Constituent ofActaea raemosaL.,” Nature 12:544-545 (1962).
Kumar, T., and Shawl, A.S., “Isoflavonoids fromIris crocea,” Phytochemistry 31: 1399-1401 (1992).
Lin, M. and Zhou, L.X., “Studies on Chemical Constituents ofBelamcanda chinensis(L.) DC (II),” Chin. Chem. Lett. 8:133-134 (1997).
Wooten, G., “The Herbal Database,” 1984, www.okanoganl.com
atural/chem/hrbdata.htm.
List, P.H. and Horhammer, L., eds., An Hagers Handbuch der Pharmazeutischen Praxis (4th ed., Springer-Verlag, Berlin, 1972), vol. 3 pp. 375-376 (in German).
Jarry, H., et al., “Treatment of Menopausal Symptoms with Extracts ofCimicifuga racemosa: In viv . . . ,” Phytopharmaka Forsch. Klin, Anwend 99-122 (1995).
Homoopathisches Arzneibuch 2000 (Deutscher Apotheker Verlag Stuttgart), entitled “Iris versicolor,”.
F. Borrelli & E. Ernst, “Cimicifuga recemosa: A systematic review of its climical efficacy,” Eur.J.Clin.Pharmacol. 58: 235-241.
J. Liu, et al., “Evaluation of Estrogenic Activity of Plant Estracts for the Potential Treatment of Menopausal Sumptoms,” J.Agric.FoodChem. 49: 2472(2001).
C. Willis, “Herb to Know—Black Cohosh—Cimicifuga racemosa,” at http://www.wisetouch.com/blackcohosh.html, published May 22, 2002.
Montemuro, Dr. Suzanne, “Alternatives to H.R.T. and the Menopausal Woman,” The Soc. of Obstetricians and Gynaecologists of Canada, 1996, Publ. May 22, 2002.
Kawase, A., et al., “Flavonoid of Iridacea. II. Chemical Structure of ao New Isoflavone Glucoside, Homotectoridin, Isolated Together with Tectoridin from the Rhizomes ofIris germanica,” Agric. & Biol. Chem. (1973), pp. 145-150, V. 37 (abstract).
Pailer, M. & Franke, F., “Constitutes ofIris germanics,” Monatsh. Chem., (1973), pp. 1394-1408, V. 104 (abstract).
Li, Y., et al., “Flavonoids ofIris dichotomaPall,” Yaoxue Xuebao, (1986), pp. 836-841, V. 21 (abstract).
Lu, Y., et al., “Quantitative Analysis for the Three Main Isoflavonoids in the Chinese Drug, Shegan, by TLC/HPLC-Densitometry,” Yaowu Fenxi Zazhi, (1987), pp. 275-279 V. 7, abstract.
Huang, M., “Studies on the TLC and Assay ofBelamcanda chinensis(L.) DC,Iris tectorumMaxim andIris dichotomaPall,” Yaowu Fenxi Zazhi, (1997), pp. 112-115, V. 17 (abstrac.
Eskai, S., et al., “Physiological Studies on Tectoridin and Tectorigenin,” Nippon Yakurigaku Zasshi, (1968), pp. 186-198, V. 64 (in Japanese), entire article.
Web page: “Garden Web's Hortiplex Plant Database”, at: http://hortiplex2.gardenweb.com/plants/p1/gw1020997/html—accessed Dec. 19, 2004.
Web page: “Iris pallida illyrica”, at: http://www.zaplana.net/flowers/asp/display—flower [Zaplana.net]—accessed Dec. 16, 2004.
Diel, P. et al., “Ability of xeno- and pythoestrogens to odulate expression of estrogen-sensitive genes in rat uterus . . . ,” J. Steroid Biochem.Mol.Biol. 73:1-10 (2000).
Whitten, P. & H.B. Patisaul, “Cross-species and interassy comparisons of phythoestrogen action,” Environ.Health Perspect. 109s1: 5-20 (2001).
Blaschek, W. et al., eds., “Drogen A-K”, Folgeband 2 (Springer-Verlag, Berlin, 1998), pp. 374-378 (in German).
Pschyrembel, “Wörterbuch Naturheilkunde und alternative Heilverfahren” (Walter de Gruyter, Berlin, 1996), p. 52 (in German).
Ezaki, S., “Pharmacological Effects of Tectoridin and Tectorigenin,” J. Japan Pharmacol. Assoc. (1968), 64:186-198.
S. Ezaki, “Pharmacological Studies of Tectoridin and Tectorigenin,” Nippon Yakurigaku Zasshi 64: 186-198 (1968) (original publication in Japanese), Chemical Abstracts, v. 69, p. 9822, Abstract No. 104972j.
J.X. Li et al., “Anti-Osteoporotic Activity of Traditional Medicines—Active Constituents of Cimicifugae Rhizome,” J. Tradit. Med. 12:816-817 (1995).
H. Jarry & G. Harnischfeger, “Studies on the Endocrine Effects of the Contents ofCimicifuga racemosa1. Influence on the Serum Concentration of Pituitary Hormones in Ovariectomized Rats,” Planta Medica 1:46-49 (1985).
H. Jarry et al., “Studies on the Endocrine Effects of the Contents ofCimicifuga racemosa2: In Vitro Binding of Compounds to Estrogen Receptor,” Planta Medica 4:316-319 (1985).
E.-M. Duker et al., “Effects of Extracts ofCimicifuga racemosaon Gonadotropin Release in Menopausal Women and Ovariectomized Rats,” Planta Med. 57:420-424 (1991).
Revilla et al., “Comparison of Several Procedures Used for the Extraction of Anthocynains from Red Grapes,” J.
Christoffel Volker
Jarry Hubertus
Spengler Barbara
Wuttke Wolfgang
Bionorica AG
Catalyst Law Group APC
Farber Michael B.
Hoffman Susan C
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