Use of excitatory opioid receptor antagonists to prevent growth

Details Use of excitatory opioid receptor antagonists to prevent growth Use of excitatory opioid receptor antagonists to prevent growth

1993-08-13

1996-12-17

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, A61K 3800

Patent

active

055853480

ABSTRACT:
This invention relates to a method of preventing hyperalgesia and other undesirable side-effects associated with the administration of growth factor, including nerve growth factor, utilizing an antagonist capable of inactivating excitatory opioid receptor-mediated functions on neurons in the nociceptive pathway. In addition, this invention relates to a composition comprising a growth factor and an antagonist capable of inactivating excitatory opioid receptor-mediated functions on neurons in the nociceptive pathway.

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