Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1981-07-07
1984-04-03
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
424 45, 424 59, 424227, 424230, 424238, 424244, 424258, 424273R, 424278, 424279, 424310, 424315, 424316, 424317, A61K 3119, A61K 3140
Patent
active
044407777
ABSTRACT:
Greatly enhanced delivery of a wide variety of bio-affecting agents is provided by formulations for topical application comprising at least one bio-affecting agent and eucalyptol. Optionally, the formulation can further comprise a non-toxic topical carrier and/or an additional penetration enhancer. The eucalyptol acts as a unique transport agent which readily delivers the active bio-affecting agent across the stratum corneum to the target area. Cosmetic and therapeutic dermatological agents as well as systemically effective therapeutic agents can be easily formulated with eucalyptol and effectively delivered through the skin to the desired site, i.e., to the underlying tissues of the epidermis and dermis or to the general circulation.
REFERENCES:
patent: 3472931 (1969-10-01), Stonghton
patent: 3527864 (1970-09-01), MacMillan et al.
Chem. Abst., vol. 94 (1981), 145378e.
Merck Index, 9th Ed..COPYRGT.1976, 520, 649, 656657,834 1164.
Proceedings of Joint Conf. on Cosmetic Sciences, 1968, pp. 189-203, Robert J. Feldmann & Howard I. Maibach.
The Extra Pharmacopoeia, Martindale, pp. 1461-1463, 27th Edition, 1977.
Friedman Stanley J.
Merck & Co. , Inc.
Monaco Mario A.
Polk Manfred
Sudol, Jr. Michael C.
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