Use of etilefrin and etilefrin pivalate in the long term treatme

Details Use of etilefrin and etilefrin pivalate in the long term treatme Use of etilefrin and etilefrin pivalate in the long term treatme

1985-04-19

1987-05-05

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

A61K 31135

Patent

active

046633545

ABSTRACT:
The use of etilefrin or etilefrin pivalate in the long term treatment of circulatory disorders not due to hypotonia, such as for example peripheral arterial stenoses, leads surprisingly to a continuous stable rise in systolic blood pressure and blood pressure amplitude and an improved cardiac output, without affecting the diastolic blood pressure or the cardiac frequency. The pharmaceutical effect is enhanced by using etilefrin in combination with an extract of horse chestnut seeds in a long term treatment.

REFERENCES:
patent: 4374841 (1983-02-01), Descamps et al.
Textbook of Medicine; Cecil, 16th Ed. (1982), p. 2120.
Medical Botany (1977), Walter H. Lewis, pp. 189-190.
Chemical Abstracts, vol. 83 (1975), #37898p; Coleman et al.

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