Use of electromagnetic fields in cancer and other therapies

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Thermal applicators

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C607S102000

Reexamination Certificate

active

06856839

ABSTRACT:
Methods and apparatus are described for the treatment of diseases by exposures to electromagnetic fields. Also, apparatus is described for focusing the biological effectiveness of such fields on specific cells, tissues or organs of a human or animal body.

REFERENCES:
patent: 4800899 (1989-01-01), Elliott
patent: 4815446 (1989-03-01), McIntosh
patent: 5450859 (1995-09-01), Litovitz
patent: 5544665 (1996-08-01), Litovitz
patent: 5566685 (1996-10-01), Litovitz
patent: 5780971 (1998-07-01), Dawson et al.
patent: 5968527 (1999-10-01), Litovitz
patent: 6142939 (2000-11-01), Eppstein et al.
patent: 6238872 (2001-05-01), Mosseri
patent: 6246912 (2001-06-01), Sluijter et al.
patent: 6251128 (2001-06-01), Knopp et al.
patent: 6259952 (2001-07-01), Sluijter et al.
patent: 6301506 (2001-10-01), den Boer et al.
patent: 6331774 (2001-12-01), Stern
patent: 6451013 (2002-09-01), Bays et al.
patent: 6561968 (2003-05-01), Dissing et al.
patent: 6595934 (2003-07-01), Hissong et al.
Gordon SA, et al., “Induction of heat shock protein 70 protects thymocytes against radiation-induced apoptosis,” Arch. Surg. 1997; 132:1277-82.
Ueno S. et al. “Vectorial magmatic stimulation or the human brain.” in Electricity and Magnetism in Biology and Medicine, Blank M. Ed. San Francisco Press. Inc. CA. p. 733-4, 1993.
Walker DM, et al., “Heat stress limits infarct size in the isolated perfused rabbit heart,” Cardiovose. Res. 1993;27:962-967.
Watters D, “Molecular mechanisms of ionizing radiation-induced apoptosis.” Immunol. Cell Biol. 1999;77;263-71.
Aquino DA, et at., “Multiple sclerosis: altered expression of 70-and 27-jDa hear shock proteins in lesions and myelin,” J. Neuropathol. Exp. Neurol. 1997;56(6):664-672.
Birnbaum G, et al., “Heat shock or stress proteins and their role as auto-antigens in multiple sclerosis,” Ann. NY Acad. Sci. l997;835:157-167.
Blank M, et at., “Changes in polypeptide distribution stimulated by different levels of electromagnetic and thermal stress,” Bioelectrochemistry and Bioenergetics 1994;33:109-114.
Boehncke WH, et at., “Differential expression heat shock protein 70 (HSP7O) and heat shock cognate proteins 70 (HSC7O) in human epidermis,” Arch. Dermatol. Res. 1994; 287(l):68-71.
Borrelli Mi, eta!., “Thermotolerance expression in mitotic CHO cells without increased translation of heat shock proteins,” J. Cell Physiol. 1988;169:420-8.
Cadossi R, et a!., “Effect of low frequency low energy pulsing electromagnetic fields on mice injected with cyclophosphamide,” Exp. Hematol. 1991;19:196-201.
Chang BK, el a!., “Inhibition of DNA synthesis and enhancement of the uptake and action of methotrexate by low-power-density mucrowave radiation in L1210 leukemic cells,” Cancer Res. 1980;40:1002-l005.
Currie RW, et al., “Heat-shock response is associated with enhanced postischemic ventricular recovery” Circ.Res. 1988;63:543-549.
Detlavs I, et al., “Experimental study of the effects of radiofrequency electromagnetic fields on animals with soft tissue wounds,” Sci.Total.Environ. 1996;180:35-42.
Di Carlo AL, et al., Myocardial protection conferred by electromagnetic fields,) Circulation 1999;99:813-816.
Di Carlo AL, et al., “Short-Term Magnetic Field Exposures (60 Hz) Induce Protection Against Ultraviolet Radiation Damage,” lnt.J.Radiat.Biol. 1998;75: 1541-1550.
Dindar H, et al., “The effect of electromagnetic field stimulation on corticosteroidsinhibited intestinal wound healing,” Tokai.J.Exp.Clin.Med. 1993; l8:49-55.
Donnelly TJ, el al., “Heat shock protein induction in rat hearts. A role for improved myocardial salvage after ischemia and reperfusion?,” Circulation 1992;85:769-778.
Essele KP, at al., “Coil optimization for neural stimulation with magnetic field,” in Electricity and Magnetism in Biology and Medicine, Blank M, Ed. San Francisco Press, Inc. CA. p. 736-7, 1993.
Fitzsimmons RJ, et at., “Embryonic bone matrix formation is increased after exposure to a low-amplitude capacitively coupled electric field, in vitro,” Biochim. Biophys. Acta 1986;882:51-56.
Fuks Z, et al., “Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in viva,” Cancer Res. 1994;54:2582-90.
Goodman R, et al, “Increased levels of HSP7O transcripts induced when cells are exposed to low frequency electromagnetic fields,” Bioelectrochemistry and Bioenergetics I 994;33: 115-120 Gordon, SA, et al., “Induction of heat shock protein 70 protects thymocytes against radiation-induced apoptosis,” Arch. Surg. 1997; 132:1277-82.
Han L, et al., “Application of magnetic field-induced heat shock protein 70 for presurgical cytoprotection,” J.Cell Biochem. 1998;71 :577-583.
He L et al., “Variation of heat shock protein 70 through the cell cycle in HL-60 cells and its relationship to apoptosis,” Exp. Cell Res. 1997;232:64-71.
Hutter MM, at al., “Heat-shock protein induction in rat hearts. A direct correlation between the amount of heat-shock protein induced and the degree of myocardial protection,” Circulation 1994;89:355-360.
Iwak K, et al., “Induction of HSP7O in cultured rat neonatal cardiomyocytes by hypoxia and metabolic stress,” Circulation 1993;87:2023-2032.
Kang KI, et al., “Luciferase activity and synthesis of Hsp7O and Hsp9O are insensitive to 50Hz electromagnetic fields,” Life Sci. 1998;63:489-97.
Korner G, et al., “Effects of ionizing irradiation on endothelial cell transqlutaminase,” FEBS Lett. 1993;330:41-5.
Lin H, et al.,“Electromagnetic field exposure induces rapid, transitory heat shock factor activation in human cells” J.Cell Biochem. 1997;66:482-488.
Martin DF, et al., “Radiation sensitivity of cultured rabbit aortic endothelial cells,” IJROBP 1984;10:1903-6.
Matsumoto H, et al., “Suppression of heat-induced p53 accumulation and activation by CDDP orx-rays in human glioblastoma cells,” Int. J. Oncol. 1998;13(4):741-7.
McCleary VL, et al., “Low magnetic field effects on embryonic bone growth,” Biomed.Sci.lnstrum. 1991;27:205-217.
McMillan DR, et al., “Targeted disruption of heat shock transcription factor I abolishes thermotolerance and protection against heat-inducible apoptosis,” J. Biol. Chem. 11998;273:7523-8.
Mestril R, el al., “Expression of inducible stress protein 70 in rat heart myogenic cells confers protection against simulated ischemia-induced injury,” J.Clin.lnvest. 1994;93:759-767.
Mestril R, et al., “Heat shock proteins and protection against myocardial ischemia,” J.Mol.CellCardiol. 1995;27:45-52.
Miyakoshi, J.M., et al., “Long-term Exposure to a Magnetic Field (5 mT at 60Hz) Increases X-ray-induced Mutations,” J. Radiat. Res., 1999;40: 13-21.
Morimoto R, et al., “Cell-specific expression of heat shock proteins in chicken reticulocytes and lymphocytes,” J.Cell Biol. 1984;99: 1316-1323.
Ormote Y, et al., “Treatment of experimental tumors with a combination of a pulsing magnetic field and an antitumor drug,” Jpn. J. Cancer Res. 1990;81:956-961.
O'Rourke JF, et al., “X-irradiation-and carcinogen-induced proteins in cultured CHO cells,” Biochem. Soc. Trans. 1992;20(l):745.
Pasquinelli P, et al., “Biological effects of PEMF (pulsing electromagnetic field): An attempt to modify cell resistance to anticancer agents,” J. Environ. Pathol. Toxicol. Oncol. 1993;12(4):193-197.
Qi F, et al., “Functional and morphological damage of endothelium in rabbit ear artery following irradiation with cobalt 60,” Br. J. Pharmacol. 1998;123:653-60. Ritossa FM,“A new puffing pattern induced by heat shock and DNP in Drosophila,” Esperentia 1962;18:571-573.
Ruiter GA, et al., “Alkyl-lysophospholipids

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of electromagnetic fields in cancer and other therapies does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of electromagnetic fields in cancer and other therapies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of electromagnetic fields in cancer and other therapies will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3470671

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.