Use of DL-(+/-)-.alpha.-lipoic acid, D-(+)-.alpha.-lipoic acid,

Details Use of DL-(+/-)-.alpha.-lipoic acid, D-(+)-.alpha.-lipoic acid, Use of DL-(+/-)-.alpha.-lipoic acid, D-(+)-.alpha.-lipoic acid,

1995-11-08

1997-07-22

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 31385

Patent

active

056504292

ABSTRACT:
The invention relates to the use of DL-(+/-)-.alpha. lipoic acid, D-(+)-.alpha.-lipoic acid, L-(-)-.alpha.-lipoic acid in reduced or oxidized form or of the metabolites and salts, esters, amides thereof for the preparation of medicines for the treatment of disorders caused by changes or disturbances in the rheological properties of the blood such as blood viscosity, erythrocyte flexibility and the aggregation of erythrocytes, in particular for the treatment of microangiopathy with disturbed microcirculation. It can also be used in the treatment of diabetics and of dialysis patients for protection of the erythrocytes, in central and peripheral circulatory disturbances and in tinnitus and hearing loss.

REFERENCES:
patent: 5318987 (1994-06-01), Weithmann et al.
The Merck Index, 11th edition, p. 1469, cit#9255 1989.
WPI Abstract of Canadian Patent 2133861 (Koel Tringer) Apr. 1995.

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