Use of demineralized bone matrix in the repair of segmental defe

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone

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623 66, 427 2, 514 21, 530840, A61F 228, A61K 3512, A01N 102

Patent

active

049022962

ABSTRACT:
A grafting material comprising milled bone which has an initial coating of guanidine-extracted bone proteins which are dialyzed from solution. Unbound bone proteins are removed and this augmented milled bone is lyophized. A subsequent coat of anti-coagulated plasma containing plasma proteins is applied to the augmented milled bone. The unbound plasma proteins are removed from the coating by rinsing.

REFERENCES:
patent: 4294753 (1981-10-01), Urist
patent: 4330891 (1982-05-01), Branemark et al.
patent: 4378803 (1983-04-01), Takagi et al.
patent: 4472840 (1984-09-01), Jefferies

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