Use of decreased 3-alpha-hydroxysteroid dehydrogenase activity i

Details Use of decreased 3-alpha-hydroxysteroid dehydrogenase activity i Use of decreased 3-alpha-hydroxysteroid dehydrogenase activity i

1993-12-17

1994-12-27

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving oxidoreductase

435 4, 435810, 435975, 436 63, 436808, 514912, 514913, C12Q 132, G01N 3348

Patent

active

053765346

ABSTRACT:
An assay for determining patients either having Primary Open Angle Glaucoma or at risk of developing Primary Open Angle Glaucoma. The assay involves testing cells, preferably lymphocyte cells, for 3.alpha.-HSD activity and determining from the level of assayed activity whether the patient is either suffering from Primary Open Angle Glaucoma or at risk therefor.

REFERENCES:
patent: 4863912 (1989-09-01), Southren et al.
Southren et al, Chemical Abstracts, vol. 100, p. 321, Ref. #32937k, 1984 (Invest. Opthalmol. Visual Sci. 1983, 24(10), 1413-17).

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