Use of cyanoacrylate adhesive compositions to inhibit acute radi

Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic...

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514528, A61K 3174, A61K 3178

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active

055543650

ABSTRACT:
Disclosed are methods for inhibiting acute and/or late radiation/induced skin damage during treatment of a patient with ionizing radiation by application of a layer of cyanoacrylate adhesive to the skin surface prior to exposure of the surface to ionizing radiation.

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Sitton, Early and Late Radiation-Induced Skin Alterations Part I: Mechanisms of Skin Changes, Oncology Nursing Forum, 19(5):801-807 (1992).
Sitton, Early and Late Radiation-Induced Skin Alterations Part II: Nursing Care of Irradiated Skin, Oncology Nursing Forum, 19(6):907-912 (1992).
Dini, et al., Management of Acute Radiodermatitis, Cancer Nursing, 16(5):366-370 (1993).
Perez, et al., Principles and Practice of Radiation Oncology, Second Edition, J. B. Lippincott Company, Philadelphia, PA, pp. 104-105 (1987).
Rubin et al., Skin and Adnexa, Clinical Radiation and Pathology, Chapter 3, pp. 62-119 (1986).

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