Use of cross-linked amylose as a matrix for the slow release of

Details Use of cross-linked amylose as a matrix for the slow release of Use of cross-linked amylose as a matrix for the slow release of

1994-02-09

1995-10-10

Bleutge, John C.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424484, 424485, 424486, 424487, A61K 926

Patent

active

054569214

ABSTRACT:
The present invention is concerned with a solid slow release oral pharmaceutical dosage unit which comprises a solid dosage unit made up of an admixture of a therapeutic dosage of an orally effective pharmaceutical product and a cross-linked polymer of amylose with a cross-linking agent selected from 2,3 dibromopropanol and epichlorohydrin, wherein the cross-linking of the polymer has been carried out with from about 0.1 to about 10 g of cross-linking agent per 100 g of amylose.

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patent: 4952402 (1990-08-01), Sparks et al.
patent: 5108758 (1992-04-01), Allwood et al.

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