Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Reexamination Certificate
2007-03-06
2007-03-06
Kim, Vickie (Department: 1618)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
C514S557000, C514S859000, C514S861000, C514S864000, C424S401000, C424S642000, C424S423000
Reexamination Certificate
active
11088519
ABSTRACT:
The present invention relates to the use of creatine compounds such as, for example, creatine, creatine phosphate or analogs of creatine, such as creatine-pyruvate, creatine-ascorbate, cyclocreatine, 3 guanidinopropionic acid, guanidinoacetate, homocyclocreatine, guanidino benzoates as energy generating systems and antioxidants for preservation of skin against adverse aging effects and damage secondary to insults such as harmful sun radiations, stress and fatigue. The creatine compounds which can be used in the present method include (1) creatine, creatine phosphate and analogs of these compounds which can act as substrates or substrate analogs for creatine kinase; (2) molecules that mimic the biological activity of creatine (3) molecules that modulate the creatine kinase system.
REFERENCES:
patent: 3989816 (1976-11-01), Rajadhyaksha
patent: 4017641 (1977-04-01), DiGiulio
patent: 4130667 (1978-12-01), Smith
patent: 4254105 (1981-03-01), Fukuda
patent: 4537776 (1985-08-01), Cooper
patent: 4552872 (1985-11-01), Cooper et al.
patent: 4557934 (1985-12-01), Cooper
patent: 4599379 (1986-07-01), Flesher et al.
patent: 4628078 (1986-12-01), Glover et al.
patent: 4663157 (1987-05-01), Brock
patent: 4772591 (1988-09-01), Meisner
patent: 4847069 (1989-07-01), Bissett et al.
patent: 4847071 (1989-07-01), Bissett et al.
patent: 4891227 (1990-01-01), Thaman et al.
patent: 4891228 (1990-01-01), Thaman et al.
patent: 4912248 (1990-03-01), Mueller
patent: 4960764 (1990-10-01), Figueroa, Jr. et al.
patent: 5091171 (1992-02-01), Yu et al.
patent: 5091404 (1992-02-01), Elgebaly
patent: 5321030 (1994-06-01), Kaddurah-Daouk et al.
patent: 5324731 (1994-06-01), Kaddurah-Daouk et al.
patent: 5385938 (1995-01-01), Yu et al.
patent: 5599841 (1997-02-01), Meglasson
patent: 5674703 (1997-10-01), Woo et al.
patent: 5676978 (1997-10-01), Teicher et al.
patent: 5702688 (1997-12-01), Yu et al.
patent: 5723133 (1998-03-01), Nagai et al.
patent: 5834513 (1998-11-01), Ptchelintsev et al.
patent: 5847003 (1998-12-01), Ptchelintsev et al.
patent: 5883128 (1999-03-01), Yu et al.
patent: 5886041 (1999-03-01), Yu et al.
patent: 5912272 (1999-06-01), Hoppe et al.
patent: 5925378 (1999-07-01), Carnazzo
patent: 5939078 (1999-08-01), Fujimura et al.
patent: 5989583 (1999-11-01), Amselem
patent: 6069169 (2000-05-01), Ptchelintsev et al.
patent: 6071962 (2000-06-01), Ptchelintsev et al.
patent: 6168802 (2001-01-01), Howard et al.
patent: 6242491 (2001-06-01), Kaddurah-Daouk
patent: 6261575 (2001-07-01), Hoppe et al.
patent: 6277881 (2001-08-01), Santhanam et al.
patent: 6333356 (2001-12-01), Ptchelintsev et al.
patent: 6338855 (2002-01-01), Albacarys et al.
patent: 6413552 (2002-07-01), Stoll
patent: 6479069 (2002-11-01), Hamilton
patent: 6524611 (2003-02-01), Howard et al.
patent: 6730331 (2004-05-01), Stoll
patent: 6767924 (2004-07-01), Yu et al.
patent: 2002/0044913 (2002-04-01), Hamilton
patent: 2002/0049253 (2002-04-01), Kaddurah-Daouk
patent: 2004/0029969 (2004-02-01), Blatt et al.
patent: 2004/0052749 (2004-03-01), Golz-Berner et al.
patent: 2004/0092482 (2004-05-01), Gupta
patent: 2004/0161435 (2004-08-01), Gupta
patent: 2004/0208902 (2004-10-01), Gupta
patent: 2004/0219124 (2004-11-01), Gupta
patent: 2004/0228884 (2004-11-01), Gupta
patent: 2004/0241197 (2004-12-01), Biergiesser et al.
patent: 2004/0258717 (2004-12-01), Suermann et al.
patent: 2005/0186158 (2005-08-01), Kaddurah-Daouk
patent: 2005/0186194 (2005-08-01), Kaddurah Daouk
patent: 2005/0226840 (2005-10-01), Kaddurah Daouk
patent: 2005/0227996 (2005-10-01), Kaddurah-Daouk
patent: 0043738 (1982-01-01), None
patent: 0413528 (1991-02-01), None
patent: 0465756 (1992-01-01), None
patent: 0500332 (1992-08-01), None
patent: 0565010 (1993-10-01), None
patent: 0852949 (1998-07-01), None
patent: 817749 (1959-08-01), None
patent: 2103605 (1983-02-01), None
patent: 2357970 (2001-07-01), None
patent: 06-192085 (1994-07-01), None
patent: 09-202710 (1997-05-01), None
patent: 2000-247866 (2000-09-01), None
patent: 2001-114701 (2001-04-01), None
patent: WO-90/09192 (1990-08-01), None
patent: WO-92/08456 (1992-05-01), None
patent: WO-94/16687 (1994-08-01), None
patent: WO-95/26182 (1995-10-01), None
patent: WO-96/14063 (1996-05-01), None
patent: WO-97/12591 (1997-04-01), None
patent: WO-97/17056 (1997-05-01), None
patent: WO-97/41848 (1997-11-01), None
patent: WO-97/42960 (1997-11-01), None
patent: WO-97/46231 (1997-12-01), None
patent: WO-98/28263 (1998-07-01), None
patent: WO-99/55302 (1999-11-01), None
patent: WO-99/55303 (1999-11-01), None
patent: WO-00/15187 (2000-03-01), None
patent: WO-00/40217 (2000-07-01), None
patent: WO-01/01932 (2001-01-01), None
patent: WO-02/060394 (2002-08-01), None
patent: WO-03/005988 (2003-01-01), None
Ames, Bruce N. et al, “Oxidants, antioxidants, and the degerative diseases of aging,”Proc. Natl. Acad. Sci. USA, vol. 90:7915-7922 (1993).
Bessman, Samuel P., “The Creatine-Creatine Phosphate Energy Shuttle,”Ann. Rev. Biochem., vol. 54:831-862 (1982).
Cutler, Adrian J. et al, “Properties of a Microsomal Enzyme System fromLinum usitatissimum(Linen Flax) Which Oxidizes Valine to Acetone Cyanohydrin and Isoleucine to 2-Methylbutanone Cyanohydrin,”Archives of Biochemistry and Biophysics, vol. 238(1):272-279 (1985).
Davies, Joanna M.S. et al, “Transient Adaptation to Oxidative Stress in Yeast,”Archives of Biochemistry and Biophysics, vol. 317(1):1-6 (1995).
Harman, Denham, “Free radicals in aging,”Molecular and Cellular Biochemistry, vol. 84:155-161 (1988).
O'Gorman, Eddie et al, “The role of creatine kinase in inhibition of mitrochondrial permeability transition,”FEBS, vol. 414:253-257 (1997).
Sohal, Rajindar S. et al, “Oxidative Stress, Caloric Restriction, and Aging,”Science, vol. 273:59-63 (1996).
Sohal, Rajindar S. et al, “Oxidative stress and aging in the Mongolian gerbil (Meriones unguiculatus),”Mechanisms of Ageing and Development, vol. 81:15-25 (1995).
Stadtman, Earl R., “Protein Oxidation and Aging,”Science, vol. 257:1220-1224 (1992).
Wallimann, Theo et al, “Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ‘phosphocreatine circuit’ for cellular energy homeostasis,”Biochem. J., vol. 281:21-40 (1992).
Weindruch, Richard, “Interventions Based on the Possibility That Oxidative Stress Contributes to Sarcopenia,”The Journals of Gerontology Series A, vol. 50A(Special Issue):157-161 (1995).
Wyss, Markus et al, “1-4 Creatine metabolism and the consequences of creatine depletion in muscle,”Molecular and Cellular Biochemistry, vol. 133/134:51-66 (1994).
Cuono, Charles, B. et al, “Critical Role of Phosphagens in the Energy Cascade of Cutaneous Ischemia and Protective Action of Phosphocreatine Analogues in Skin Flap Survival,”Plastic and Reconstructive Surgery, vol. 101(6):1597-1603 (1998).
Declercq, Lieve et al, “Age-dependent response of energy metabolism of human skin to UVA exposure: anin vivostudy by31P nuclear magnetic resonance spectroscopy,”Skin Research and Technology, vol. 8:125-132 (2002).
Lenz, Holger et al, “The Creatine Kinase System in Human Skin: Protective Effects of Creatine Against Oxidative and UV DamageIn VitroandIn Vivo,” The Journal of Investigative Dermatology, vol. 124(2):443-452 (2005).
Schlattner, Uwe et al, “Creatine Kinase and Creatine Transporter in Normal, Wounded, and Diseased Skin,”J. Invest. Dermatol., vol. 118:416-423 (2002).
Zemtsov, A., “A Measurement of suberythema UVA radiation effects on skin by31P magnetic resonance spectroscopy,”Photodermatology, Photoimmunology&Photomedicine, vol. 13:24-26 (1997).
Avicena & Cockfield, LLP
Avicena Group, Inc.
Hanley Elizabeth A.
Kim Vickie
Soroos Cynthia M.
LandOfFree
Use of creatine or creatine compounds for skin preservation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of creatine or creatine compounds for skin preservation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of creatine or creatine compounds for skin preservation will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3738371