Use of creatine for the amelioration of oxidative stress

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

06927231

ABSTRACT:
The present invention relates to a method of amelioring oxidative stress and stress-related degenerative processes associated with aging or various disease conditions such as cancer, neurodegenerative diseases or the dysregulation of redox-regulated physiological processes, as indicated by the prooxidative shift in the plasma thil/disulfide redox state and its consequences in conditions of elevated oxidative stress, characterized by administering creatine.

REFERENCES:
patent: 5219846 (1993-06-01), Bru et al.
patent: WO 94/16712 (1994-08-01), None
patent: WO 98/43617 (1998-10-01), None
patent: WO 99/51097 (1999-10-01), None
The therapeutic potential of oral creatine supplementation in muscle disease, WYSS, et al., Medical Hypotheses, Eden Press (no date available).

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