Use of CPG oligodeoxynucleotides to induce angiogenesis

Details Use of CPG oligodeoxynucleotides to induce angiogenesis Use of CPG oligodeoxynucleotides to induce angiogenesis

2011-05-03

2011-05-03

Minnifield, N. M (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Hormone or other secreted growth regulatory factor,...

C424S184100, C424S278100, C514S04400A

Reexamination Certificate

active

07935351

ABSTRACT:
This disclosure provides a method of inducing production of vascular endothelial growth factor by a cell. The method includes contacting the cell with a CpG oligonucleotide, thereby inducing the production of vascular endothelial growth factor by the cell. The disclosure further provides a method inducing neovascularization in a tissue. This method includes comprising introducing a CpG oligodeoxynucleotide into an area of the tissue wherein the formation of new blood vessels is desired, thereby inducing neovascularization in the area of the tissue.

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