Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-05-16
1997-09-02
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142278, 5142315, 5142355, 514 17, 514 18, 514 19, A61K 3154, A61K 31535, A61K 3800
Patent
active
056631685
ABSTRACT:
The present invention relates to the use of inhibitors of HIV aspartate proteases, such as HIV-1- or HIV-2-protease, and their salts and to prodrugs for inhibiting the growth of tumors, especially those tumors which do not respond to the inhibition of HIV aspartate proteases themselves, and in the preparation of pharmaceutical compositions intended for use in the prophylaxis and especially the treatment of tumor diseases, and to methods and pharmaceutical compositions for the treatment of tumors with those compounds.
REFERENCES:
Shoeman et al, "Potential Role of the Viral Protease in Human Immuno-deficiency Virus Type l Associated Pathogens", Medical Hypotheses 37, 137-150, 1992.
Chem. Abst. 115: 78928 (1991).
Carter et al, Chemotherapy of Cancer, 2nd ed., John Wiley & Sons, N.Y., N.Y. pp. 67-68 (1981).
Bold Guido
Cumin Frederic
Lang Marc
Regenass Urs
Rosel Johannes
Ciba-Geigy Corporation
Fishman Irving M.
Goldberg Jerome D.
Mathias Marla J.
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