Use of CGRP in treating alopecia

Details Use of CGRP in treating alopecia Use of CGRP in treating alopecia

1995-04-28

1996-10-22

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 9, 514 11, A61K 3823

Patent

active

055676790

ABSTRACT:
The present invention relates to the use of Calcitonin Gene Related Peptide (CGRP), either topically or intramuscularly, as a treatment for hair loss. The use of calcitonin or CGRP, either topically or intramuscularly, for hair loss includes the steps of preparing a liquid carrier, adding calcitonin to the carrier, injecting the mixture into a subject intramuscularly, intravascularly, intradermally or subcutaneously, and analyzing results on the subject.

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patent: 5214030 (1993-05-01), Stief
Smith et al., Cutaneous responses to vasoactive . . . , Lancet 1992; vol. 339, pp. 91-93.
Nong et al., Peptides Encoded by Calcitonin . . . , J. Immun.; vol. 143; pp. 45-49; 1989.
Foreman, Substance P and Calcitonin . . . ; Int. Archs. Allergy appl., Innun.; vol 82, pp. 366-371, 1987.
Bunker et al., Calcitonin gene-related peptide . . . , Lancet, vol. 342, pp. 80-82, 1993.
Jernbeck et al., Calcitonin gene-related peptide . . . , Plast. Reconstr. Surg., vol. 91, pp. 245-251, 1993.
Jernbeck et al., The effect of calcitoning . . . , Clinical Phys. vol. 10, pp. 335-343, 1990.
Jernbeck et al., Calcitonin gene--related peptide . . . , Plast. Reconstr. Surg. vol. 91, pp. 236-244, 1993.

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