Use of certain 9-haloprostaglandins to treat glaucoma and ocular

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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Details

514575, 514913, A61K 31215, A61K 3119

Patent

active

056272090

ABSTRACT:
9-Haloprostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.

REFERENCES:
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patent: 5093329 (1992-03-01), Woodward
Braun, et al., "Effect of ZK 110.841 on Cerebral Vascular Contraction and TXA.sub.2 -Release Caused by Thrombin-Stimulated Platelets," Archives of Pharmacology, 339 Suppl:R37(148) (1989).
Ney, "Potent Inhibition of FMLP-Induced Neutrophil Activation by the PGD.sub.2 Analogue ZK 110.841," Archives of Pharmacology, 339 Suppl:R38(150) (1989).
"New Research Drug DLO/8149" Drug License Opportunities (IMSWORLD Publications) (Jun. 25, 1990).
Nakajima et al., Graefe's Arch. Clin. Exp. Ophthalmol., 229:411-413 (1991).
Crawford et al., J. Glaucoma, 1:94-99 (1992).
Woodward et al., Invest. Ophthalmol. Vis. Sci., 31:138-146 (1990).
Goh, et al., Graefe's Arch. Clin. Exp. Ophthalmol., 227:476-481 (1989).
Goh, et al. Jpn. J. Ophthalmol., 32:471-480 (1988).

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