Use of celastrol to treat alzheimer's disease

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514177, 514168, 514171, A61K 3156

Patent

active

058801162

ABSTRACT:
The present invention provides a method for treating patients with Alzheimer's Disease which comprises administering a an effective amount of a celastrol formulation to the patients. One source of raw material for such a celastrol formulation is the root of the vine tripterygium wilfordii Hook F.

REFERENCES:
patent: 4328309 (1982-05-01), Chalmers et al.
patent: 4746674 (1988-05-01), Pierpaoli et al.
patent: 5192753 (1993-03-01), McGeer et al.
patent: 5500340 (1996-03-01), Lipsky et al.
Li X.-Y, Anti-Inflam. Components of Tript. Wilfordii Hook F. (1993) Int. J. Immunotherapy IX(3): 181-187.
McGeer et al., Anti-Inflammatory drugs & Alzheimer's Disease, (1990) Lancet 335:1037.
Evans et al., Prevalence of Alzhemier's (1989) JAMA 262(18): 2551-56.
Reisberg, ed., Alzheimer's Disease (1983) Free Press Div of MacMillan, New York City, pp. 141-148.
Sulkava et al., Prevalence of Severe Dementia in Finland (1985) Neurology 35:1025-29.
Itagaki et al., Presence of T-cytotoxic suppresor . . . in Alzheimer's (1988) Neurosci. Lett. 91: 259-64.
Rogers et al., Expression of Immune Antigens . . . Relationship to Alzheimer's (1988) Neurosci. Ag. 9:339-49.
McGeer et al., Immune System Response in Alzheimer's Disease (1989) Can. J. Neurolog. Sci. 16:516-27.
McGeer et al. Activation of complement in Alzheimer patients (1989) Neurosci. Lett. 107:341-46.
Tachibana et al., Xenon Contrast Brain Changes in Alzheimer (1984) J. Gerontol. 39(4):415-23.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of celastrol to treat alzheimer's disease does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of celastrol to treat alzheimer's disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of celastrol to treat alzheimer's disease will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1321324

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.