Use of carboxy compounds such as...

Details Use of carboxy compounds such as... Use of carboxy compounds such as...

2006-05-30

2006-05-30

Wang, Shengjun (Department: 1617)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

C514S183000, C514S506000, C514S529000, C514S649000

Reexamination Certificate

active

07053120

ABSTRACT:
The present invention relates to the use of specific carboxy compounds, more specifically to the use of 2(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride, in the treatment of inflammatory diseases. Part of the invention is also a composition, preferably a pharmaceutical composition, comprising as active ingredient at least 2 (4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride together with (pharmaceutically) acceptable excipients.

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Louw et al., Influence of an Aziridine Precursor on the In Vitro Binding Parameters of Rat and Ovine Corticosteroid Globulin, Biochemical Pharmacology, Jan. 2000, pp. 167-175, vol. 59.
Louw et al., Salsola tuberculatiformis Botschantzev and an Aziridine Precursor Analog Mediate the in Vivo Increase in Free Corticosterone and Decrease in Corticosteroid-Binding Globulin in Female Wistar Rats, Endocrinology, May 1999, pp. 2044-2053, vol. 140, No. 5.
Swart et al., Inhibition of Cytochrome P-450 11-beta by Some Naturally Occurring Acetophenones and Plant Extracts from the Shrub salsola tuberculatiformis, Planta Medica, 1993, pp. 139-143, vol. 59, No. 2.

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