Use of calcium channel blocker to prevent cocaine induced cravin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514322, 514812, A61K 31445, A61K 3144

Patent

active

051243407

ABSTRACT:
A method of treating cocaine addiction by administering to a patient in need thereof, an anti-cocaine addicting effective amount of a calcium channel blocking agent.

REFERENCES:
patent: 4797410 (1989-01-01), El-Fakahany
Barrios et al. "Differential effects of calcium channel blockers and stimulants on morphine withdrawal in vitro" Eur. J. Pharmac. 152(88) 175-178.
Chem. Abst., 105-90819n (1986).
Snyder et al., Calcium-Antagonist Drugs, 1988, N. Engl. J. Med., pp. 995-1002.
Nahas et al., Calcium-Channel Blocker as Antidote to Cardiac Effects of Cocaine Intoxication, 1988, N. Engl. J. Med., pp. 519-520.
Miller, Multiple Calcium Channels and Neuronal Function, 1987, Science, pp. 46-52.
Rowbotham et al., Cocaine-Calcium Channel Antagonist Interactions, 1987, Psychopharmacology, pp. 152-154.

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