Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2007-03-09
2011-10-04
Kim, Jennifer M (Department: 1628)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
active
08030357
ABSTRACT:
Compounds that may be used for the treatment or prevention of a condition associated with T-cell proliferation or that is mediated by pro-inflammatory cytokines are of formula (I)or a salt thereof.
REFERENCES:
patent: 2002/0052341 (2002-05-01), Fang et al.
patent: WO 01/62257 (2001-08-01), None
Brustolim et al. “A new chapter opens in anti-inflammatory treatments: The antidepressant Bupropion lowers production of tumor necrosis factor and interferon-gamma in mice”International Immunopharmacology, 2006, pp. 903-907, vol. 6.
Modell et al. “Treatment of atopic dermatitis and psoriasis vulgaris with bupropion-SR: A pilot study”Psychosomatic Medicine, 2002, pp. 835-840, vol. 64.
Bondarev, M. L. et al, “Behavioral and biochemical investigations of bupropion metabolites,”European Journal of Pharmacology, pp. 85-93, vol. 474, No. 1, Amsterdam, NL.
Kast R.E., “Evidence of a mechanism by which etanercept increased TNF-alpha in multiple myeloma: New insights into the biology of TNF-alpha giving new treatment opportunities—the role of bupropion,”Leukemia Research, Dec. 2005, pp. 1459-1463, vol. 29, No. 12, New York, NY, US.
Musso, D. L. et al, “Synthesis and evaluation of the anticonvulsant activity of a series of 2-amino-1-phenyl-1-propanols derived from the metabolites of the antidepressant bupropion,”Bioorganic&Medicinal Chemistry Letters, Jan. 7, 1997, pp. 1-6, vol. 7, No. 1, Oxford, GB.
Bannister Robin Mark
Baxter Andrew Douglas
Brew John
Biocopea Limited
Kim Jennifer M
Saliwanchik Lloyd & Eisenschenk
LandOfFree
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