Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-04-11
1999-03-02
Marschel, Ardin H.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
536 221, 536 231, 536 2532, C12Q 168, C07H 1900, C07H 2102, C07H 2100
Patent
active
058769382
ABSTRACT:
Modified nucleotides and polynucleotides which are useful in hybridization assays for the detection of target genes are provided. The modified polynucleotides contain at least one boronic acid moiety which is attached to a nucleotide base in a position which does not interfere with the hydrogen bonding capabilities of that base during duplex formation. The modified polynucleotides are typically formed from naturally occurring nucleotides and one or more modified nucleotides.
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Kaiser Robert J.
Stolowitz Mark L.
Marschel Ardin H.
Prolinx Incorporated
Riley Jezia
LandOfFree
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