Use of borate-polyol complexes in ophthalmic compositions

Details Use of borate-polyol complexes in ophthalmic compositions Use of borate-polyol complexes in ophthalmic compositions

1993-09-07

1994-08-30

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424400, 424427, 424658, 424659, 514839, 514840, 514912, 514915, A61K 908

Patent

active

053426207

ABSTRACT:
Aqueous ophthalmic compositions containing water-soluble borate-polyol complexes are useful in aqueous ophthalmic compositions containing polyvinyl alcohol. These compositions provide the benefits of a borate buffering system, such as enhanced antimicrobial activity, without the problems associated with the use of borate and pol, such as formation of borate-polyvinyl alcohol complexes which are water-insoluble.

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