Use of bismuth (phosph/sulf)ated saccharides against Camplyobact

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536 171, 536121, 536117, A61K 31715, C07H 1500, C07H 2300, C07H 1104

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active

049354060

ABSTRACT:
Bismuth (phosph/sulf)ated saccharides are useful in ameliorating gastrointestinal disorders associated with Campylobacter-like organisms such as, for example, Campylobacter pylori. For example, compositions containing a complex salt of bismuth hydroxide sucrose octasulfate can be thus employed to treat Type B gastritis.

REFERENCES:
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Bowen et al., U.S. patent application Ser. No. 07/209,372, file Jun. 21, 1988.
Graham et al., The American Journal of Gastroenterology, 82, 283-286 (1987).
Blaser, Gastroenterology, 93, 371-83 (1987).
Scrip (Dec. 3, 1986), "Anti-Ulcer Market".
Borsch, Leber, Magen, Darm.(W. Ger.), 18, 38-45 (Jan., 1988).
Anderson et al. (Eds.), Chem. Sources U.S.A., Directories Publishing Co., Inc., Ormond Beach, Fla. (1984), pp. 158, 257, 259, 262, 311, 326, 447 & 467.
Carey et al., Advanced Organic Chemistry, Part B: Reactions and Synthesis, Plenum Press, New York (1977), pp. 482-496 & 507.

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