Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-10-20
1990-07-10
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514401, A61K 31415
Patent
active
049407236
ABSTRACT:
A method of treating arthritis, and/or bone marrow hyperplasia, osteitis and synovitis, and/or granulomatosis including of the liver and spleen, which comprises administering to a patient an effective amount of BABIM and a pharmaceutically acceptable carrier.
REFERENCES:
Dieter et al. "Suppression of Streptococcal Cell Wall-Induced Arthritis by a Potent Protease Inhibitor, Bis-(5-Amidino-2-benzimidazolyl)methane", Arthritis and Rheumatism, vol. 31, No. 9 (Sep. 1988).
Jennette et al. "Amelioration of Immune Complex-Mediated Glomerulonephritis by Synthetic Protease Inhibitors", American Journal of Pathology, vol. 127, No. 3, Jun., 1987.
Gallin et al. Inflammation, Basic Principles and Clinical Correlates, Raven Press, 1988, Chapter 50 by P. E. Lipskey, "Gold, Penicillamine, and Antimalarials", pp. 897-910.
Stecher et al. "Disease-Modifying Anti-Rheumatic Drugs", Medicincal Research Reviews, vol. 5, No. 2, pp. 371-390 (1985).
Chem. Abst. vol. 108 (1988)-106095y.
Chem. Abst; vol. 109 (1988)-183228s.
Anderle Sonia K.
Geratz Joachim D.
Pryzwansky Katherine B.
Schwab John H.
Tidwell Richard R.
Friedman Stanley J.
University of North Carolina - Chapel Hill
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