Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2003-04-11
2010-11-02
Kemmerer, Elizabeth C. (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007210, C435S325000, C435S348000, C435S352000, C435S357000, C435S358000, C435S365000, C435S368000, C435S369000, C435S372100, C435S254200, C435S254210, C435S254230, C435S257600, C435S380000
Reexamination Certificate
active
07824869
ABSTRACT:
The invention is directed to a method for altering the ion conductivity of a membrane. The method comprises inserting a biological photoreceptor into the membrane. The biological photoreceptor is configured to act as a light-controlled ion channel. The photoreceptor used comprises an apoprotein and a light-sensitive polyene covalently bound to the apoprotein, wherein the polyene interacts with the apoprotein and functions as a light-sensitive gate.
REFERENCES:
patent: 4879284 (1989-11-01), Land et al.
patent: 5041224 (1991-08-01), Ohyama et al.
patent: 7144733 (2006-12-01), Miesenbock et al.
patent: 06-295350 (1994-10-01), None
Hildebrandt-K et al., PNAS, 90(3578-3582)1993.
Hildebrant et al., PNAS, USA 90:3578-3582, published Apr. 1993.
Wald G., Nature, 219(5156): 800-807, published Aug. 24, 1968.
Abdulaev NG and Ridge KD. Heterologous expresion of bovine opsin inPichia pastoris. Methods Enzymology, 2000; 315:3-11.
Han M et al. Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6. Biochemistry, 1998; 37: 8253-8261.
Muradin-Szweykowska et al, Eur. J. Biochem, 140(1): 176-176 (Apr. 2, 1984).
National Center for Biotechnology Information, “Chlamydomonas reinhardtiiacop1 mRNA for archaeal-type opsin 1, complete cds.,” Accession No. AB058890 (Mar. 26, 2002) (Accessed on the internet, Jan. 8, 2003).
National Center for Biotechnology Information, BLAST sequence comparison of Accession No. AB058890.1 with Seq ID No. 1 (Accessed on the internet, Jan. 8, 2003).
National Center for Biotechnology Information, “Chlamydomonas reinhardtiiacop2 mRNA for archaeal-type opsin 2, complete cds.,” Accession No. AB058891 (Mar. 26, 2002) (Accessed on the internet, Jan. 8, 2003).
National Center for Biotechnology Information, BLAST sequence comparison of Accession No. AB058891.1 with Seq ID No: 2 (Accessed on the internet, Jan. 8, 2003).
Bieszke et al.,Proc. Natl. Acad. Sci., 96, 8034-8039 (1999).
Hegemann et al.,Journal of Phycology, 37, 668-676 (2001).
Nagel et al.,Science, 296, 2395-2398 (2002).
Perozo et al.,Biochemistry, 32, 10471-10478 (1993).
Sineshchekov et al.,Proc. Natl. Acad. Sci., 99 (13), 8689-8694 (2002).
European Bioinformatics Institute, “Chlamydomonas reinhardtiichannelopsin 1 precursor, mRNA, complete cds.,” Accession No. XP-002533269 (Oct. 2, 2001) (Accessed on the internet, Jun. 22, 2009).
Bamberg Ernst
Hegemann Peter
Nagel Georg
Ballard Kimberly A.
Kemmerer Elizabeth C.
Leydig , Voit & Mayer, Ltd.
Max-Planck-Gesellschaft zur Foerderung der Wissenschaften E.V.
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