Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-03-28
2006-03-28
Wilson, James O. (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S075000, C514S012200, C514S231500, C514S233500, C514S381000, C536S123100, C536S123120, C536S124000, C435S069100, C435S320100, C424S130100, C424S165100, C424S169100, C424S442000
Reexamination Certificate
active
07018986
ABSTRACT:
The invention provides methods of using beta glucans to treat conditions associated with bone loss or low bone density as well as methods for promoting bone growth in situations where enhanced bone growth is desirable. In the invention methods beta glucans are administered so as to enhance the development of osteoblasts and the inhibition of the development and recruitment of osteoclasts. The inhibition of the recruitment and development of osteoclasts, coupled with the enhancement of osteoblast maturation by beta glucans leads to decreased bone resorption and increased bone formation, making beta glucans ideal agents for the treatment of osteoporosis and other bone resorption diseases.
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patent: 4739046 (1988-04-01), Di Luzio
patent: 5622940 (1997-04-01), Ostroff
patent: 6117850 (2000-09-01), Patchen et al.
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Bahl Arun K.
Guenther Hannelore E.
Guenther Harald L.
Sorgente Nino
DLA Piper Rudnick Gray Cary US LLP
Immudyne
Khare Devesh
Wilson James O.
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