Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1995-07-28
1997-01-07
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
604 51, 623 11, 623 15, A61F 202, A61F 210, A61M 3100
Patent
active
055914446
ABSTRACT:
The application concerns a method of repairing subcutaneous or dermal tissue in a subject. The method involves the preparation of cultured dermal fibroblasts from a specimen obtained from the subject and the injection of the fibroblast preparation, substantially free of immunogenic proteins, to repair the subcutaneous or dermal tissue. The method is applicable to the repair of rhytids, stretch marks, depressed scars, and non-traumatic cutaneous depressions as well as to the cosmetic augmentation of the lips.
REFERENCES:
patent: 3949073 (1976-04-01), Daniels et al.
patent: 4424208 (1984-01-01), Wallace et al.
patent: 4488911 (1984-12-01), Luck et al.
patent: 4582640 (1986-04-01), Smestad et al.
patent: 4642117 (1987-02-01), Nguyen et al.
patent: 4969912 (1990-11-01), Kelman et al.
patent: 5002071 (1991-03-01), Harrell
patent: 5332802 (1994-07-01), Kelman et al.
patent: 5366498 (1994-11-01), Brannan et al.
Spira and Rosen, "Injectable Soft Tissue Substitutes", Clin Plastic Surgery 20:181-189 (1983).
Matton et al., "The History of Injectable Biomaterials and the Biology of Collagen", Aesthetic Plastic Surgery 9:133-140 (1985).
Nicolle et al., "Correction of Age--and Disease-Related Contour Deficiencies of the Face", Aesthetic Plastic Surgery 9:159-162 (1985).
Pieyre, "Collagen Injections: Two Years' Experience", Aesthetic Plastic Surgery 9:153-154 (1985).
DeLustro et al., "Reaction to Injectable Collagen: Results in Animal Models and Clinical Use", Plastic and Reconstructive Surgery 79:581-592 (1987).
"Treatment of Depressed Cutaneous Scars with Gelatin Matrix Implant: A Multicenter Study", J Am Acad Dermatol 16:1155-1162 (1987).
Matti and Nicolle, "Clinical Use of Zyplast in Correction of Age--and Disease-Related Contour Deficiencies of the Face", Aesthetic Plastic Surgery 14:227-234 (1990).
Ersek, "Transplantation if Purified Autologous Fat: A 3-Year Follow-Up is Disappointing", Plastic and Reconstructive Surgery 87:219-227 (1991).
Millikan et al., "A 5-Year Safety and Efficacy Evaluation with Fibrel in the Correction of Cutaneos Scars Following One or Two Treatments", J Dermatol Surg Oncol 17:223-229 (1991).
Gonzalez Ulloa, "The Sensuous Lip", Aesthetic Plastic Surgery 16: 231-236 (1992).
Hambley and Carruthers, "Micropoinjection for the Elevation of Depressed Full-Thickness Skin Grafts on the Nose", J Dermatol Surg Oncol 18:963-968 (1992).
Lewis, "The Current Status of Autologous Fat Grafting", Aesthetic Plastic Surgery 17:109-112 (1993).
Gold, "The Fibrel Mechanism of Action Study. A Preliminary Report", J Dermatol Surg Oncol 20:586-590 (1994).
McKinney and Pandya, "Use of Public Fat as a Graft for Eyelid Defects", Aesthetic Plastic Surgery 18:383-385 (1994).
Ozgentas et al., "A Comparison of Soft-Tissue Substitutes", Ann Plastic Surgery 33(2):171-177 (1994).
Davies et al., "Autologous Free Dermal Fat Graft. Reconstruction of Facial Contour Defects", Arch Otolaryngol Head Neck Surg 121:95-100 (1995).
Azpuru Carlos
Isolagen Technologies, Inc.
LandOfFree
Use of autologous dermal fibroblasts for the repair of skin and does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of autologous dermal fibroblasts for the repair of skin and , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of autologous dermal fibroblasts for the repair of skin and will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1762328