Use of at least one extract of a plant of the genus Lannea...

Details Use of at least one extract of a plant of the genus Lannea... Use of at least one extract of a plant of the genus Lannea...

2002-04-17

2003-07-29

Prats, Francisco (Department: 1651)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

C424S401000

Reexamination Certificate

active

06599537

ABSTRACT:

BACKGROUND OF THE INVENTION
This invention relates generally to the field of cosmetics and pharmacology and more particularly to the use of at least one extract of a plant belonging to the genus Lannea, preferably
Lannea coromandelica
or
Lannea grandis,
in cosmetic or dermopharmaceutical preparations.
Lannea coromandelica
(Houtt.) Merr. is a tree originating from the Anacardiaceae family which is encountered mainly in India and in various Asiatic countries.
In the books of traditional Indian medicine, it is sometimes confused with
Lannea grandis
because, in many works, both have the same synonym Odina woodier roxb.
The bark is traditionally used in particular in the treatment of cuts, other wounds, bruises (sprains and strains) and diarrhoea, aqueous extracts of the bark also being used as an abortive.
The leaves like the bark are also used as curatives, particularly in the treatment of inflammation, arthritis, bruises and, generally, physical pain.
It is known that an ethanol extract of
Lannea coromandelica
leaves has a protective effect on the membrane of the red blood cells against hypotonic stress which has been taken as an indication of anti-inflammatory activity (cf. Gandhidasan R. et al., Fitoterapia, 62/1, 81-83, 1991).
In addition, an ethanol-containing extract of the bark, after intraperitoneal administration, has been shown to have quite considerable anti-inflammatory activity in doses dependent upon the particular type of inflammation, this extract having no pain-killing (analgesic) or antipyretic activity (cf. Singh S. and Singh G. B., Phytotherapy Research, 8/5, 311-313,1994).
By contrast, the inventors have found that, besides the therapeutic properties mentioned above, extracts obtained from various parts of the plant also have significant biological properties so that they may be directly used in cosmetic and dermopharmaceutical compositions or for the preparation thereof.
The effects and properties demonstrated so unexpectedly and surprisingly consist in antiradical-like, cytophotoprotective, tyrosinase- and melanogenesis (depigmenting)-inhibiting and antiprotease (antielastase, anticollagenase) effects.
BRIEF SUMMARY OF THE INVENTION
Accordingly, the problem addressed by the present invention was in particular to use at least one extract of a plant belonging to the botanical genus Lannea, preferably
Lannea coromandelica
or
Lannea grandis
(synonym Odina woodier), as an active principle for the preparation of a cosmetic product for external use for the skin, the mucous membranes and/or the epithelial appendage (superficial body growth), the extract or extract mixture in question being usable on its own or together with at least one other active principle.


REFERENCES:
patent: 07010765 (1995-01-01), None
The Wealth of India, 1962, vol. VI, Council of Scientific and Industrial Research, New Delhi, pp. 27-29.*
Singh et al., “Anti-inflammatory Activity ofLannea coromandelicaBark Extract in Rats”, pp. 311-313, vol. 8, Phytotherapy Research, (1994).
Gandhidasan et al,. “Anti-inflammatory Action ofLannea Coromandelicaby HRBC Membrane Stablization”, pp. 81-83, vol. 62, Fitoterapia, (1991).
Chemical Abstracts, p. 372, vol. 122, No. 15, Columbus OH, 1995.
Groweiss et al., “Novel Cytotoxic, Alkylated Hydroquinones fromLannea welwitschii”, pp. 116-121, vol. 60, No. 2, Journal of Natural Products, (1997).

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