Use of antiprogestins for prophylaxis and treatment of...

Details Use of antiprogestins for prophylaxis and treatment of... Use of antiprogestins for prophylaxis and treatment of...

2008-05-27

2008-05-27

Hui, San-Ming (Department: 1617)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

Reexamination Certificate

active

07378406

ABSTRACT:
The present invention relates to methods and uses for preventing or treating hormone-dependent disease, in particular breast cancer, in a mammal by antiprogestins, in particular antiprogestin 11β-(4-acetylphenyl)-17β-hydroxy-17α-(1,1,2,2,2-pentafluoroethyl)-estra-4,9-dien-3-one or a pharmaceutically acceptable derivative or analogue thereof. The invention further relates to pharmaceutical compositions comprising said antiprogestin.

REFERENCES:
patent: 6316432 (2001-11-01), Schwede et al.
patent: 6503895 (2003-01-01), Schwede et al.
patent: 6806263 (2004-10-01), Schwede et al.
patent: 7148213 (2006-12-01), Schwede et al.
patent: 2280041 (1998-08-01), None
patent: 19706061 (1998-08-01), None
Fuhrmann Ulrike et al., “Synthesis and Biological Activity of a Novel, Highly Potent Progesterone Receptor Antagonist,” Journal of Medical Chemistry, Dec. 7, 2000, pp. 5010-5016, vol. 43, No. 26, XP001064233, ISSN: 0022-2623, the whole document, American Chemical Society, Washington, DC.

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