Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds hormone or other secreted growth regulatory factor,...
Patent
1996-10-23
2000-05-23
Budens, Robert D.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds hormone or other secreted growth regulatory factor,...
4241461, 4241481, 4241601, 53038826, 5303891, A61K 39395, C07K 1640
Patent
active
060663235
ABSTRACT:
Sialic acids have the ability to prevent hyposialylation of cells as comptive inhibitors of endogenous sialidase. It is now also possible to develop antibodies to mammalian sialidase that significantly reduce influx of neutrophils into inflammatory sites.
REFERENCES:
patent: 5631283 (1997-05-01), Cross et al.
Daar et al., Proc. Natl. Acad. Sci. USA 87:6574-6578, Sep. 1990.
Fahey et al., Clin. Exp. Immunol. 88:1-5, 1992.
Fox, J.L., Bio/Technology, 12:128, Feb. 1994.
Haynes et al., Ann. Med. 28:39-41, 1996.
Stamatos et al., J. Cell. Biochem. Suppl. 0 (16, Part E), p. 56, Abstract Q 348, Mar. 27, 1992.
Cross Alan S.
Gomatos Peter
Stamatos Nicholas
Budens Robert D.
Harris Charles H.
Moran John Francis
The United States of America as represented by the Secretary of
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