Use of antibodies specific to human complement component C5 for

Details Use of antibodies specific to human complement component C5 for Use of antibodies specific to human complement component C5 for

1994-05-02

2000-06-13

Feisse, Lila

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

4241301, 4241401, 4241411, 4241521, 4241581, A61K 39395

Patent

active

060746424

ABSTRACT:
The use of anti-C5 antibodies, e.g., monoclonal antibodies, to treat glomerulonephritis (GN) is disclosed. The administration of such antibodies at low dosage levels has been found to significantly reduce glomerular inflammation/enlargement and other pathologic conditions associated with GN.

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patent: 5135916 (1992-08-01), Sims
patent: 5173499 (1992-12-01), Sindelar et al.
patent: 5506247 (1996-04-01), Sindelar et al.
patent: 5635178 (1997-06-01), Sims et al.

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