Use of anti-HIV IGA antibodies for producing immunological prote

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

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435 696, 435 7021, 4241331, 4241421, 5303873, C12N 506, C12P 2104, C12P 2108, A61K 39395

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active

061241326

ABSTRACT:
The subject invention concerns the production and novel use of human anti-HIV IgA antibodies to confer passive immunity to HIV when administered in vivo to a subject. The IgA antibodies of the subject invention are selectively transported to and secreted in the mucosal tissue of the subject. The IgA antibodies can confer protection from HIV infection at locations within the body where HIV penetration usually occurs.

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