Use of amines

Details Use of amines Use of amines

2006-06-13

2006-06-13

Davis, Brian (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

C514S669000, C514S670000, C564S503000, C564S504000, C564S506000, C564S507000

Reexamination Certificate

active

07060731

ABSTRACT:
This application relates to the use of certain amines of formula (I)for combatting and preventing systemic and local complement activation, and in particular to the use of meglumine and derivatives and optionally salts thereof in combatting and preventing said activation. The amines are also of use in combatting activation of the kinin/kallikrein system or blood coagulation system.

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patent: WO 99/41233 (1999-08-01), None
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C. Corot, et al. “In vitro comparison of the effects of contrast media on coagulation and platelet activation” Blood Coagulation and Fibrinolysis vol. 7, 1996, pp. 602-608.
K. Himi, et al. “Effects of ionic and nonionic contrast media on blood coagulation system, fibrinolytic system, and platelet” Database CAPLUS (online) Chemical Abstracts Service, Columbus, Ohio, US Database Accession No.: 1992-54687, Nippon Igaku Hoshasen Gakkai Zasshi (1991) 51 (a), 1037-44.
H. M. Hoffmeister, et al. “Changes in complement components after intravascular application of contrast media” Advances in Experimental Medicine and Biology, Kinins V Part B vol. 247b, 1989, pp. 585-589.

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